Literature DB >> 23252654

A case of corneal endotheliitis with mumps virus RNA in aqueous humor detected by rt-PCR.

Kiyomu Ando1, Mami Ishihara, Yoshifumi Kusumoto, Etsuko Shibuya, Satoshi Nakamura, Nobuhisa Mizuki.   

Abstract

PURPOSE: To report a case of corneal endotheliitis following the mumps parotitis.
METHODS: A 46-year-old man noticed ciliary infection and visual loss in the right eye after mumps parotitis. To determine the cause of the disease, reverse transcription-polymerase chain reaction (RT-PCR) was used to amplify mumps virus RNA in samples from the aqueous humor.
RESULTS: RT-PCR revealed mumps virus RNA in an aqueous humor sample. Although full recovery of vision was achieved within 1 month of the onset, corneal endothelial cells were severely damaged.
CONCLUSIONS: The authors have detected mumps virus in the aqueous humor by RT-PCR for the first time.

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Year:  2012        PMID: 23252654     DOI: 10.3109/09273948.2012.747619

Source DB:  PubMed          Journal:  Ocul Immunol Inflamm        ISSN: 0927-3948            Impact factor:   3.070


  2 in total

1.  Multimodal imaging in a case of bilateral outer retinitis associated with mumps infection.

Authors:  Rim Kahloun; Hager Ben Amor; Imen Ksiaa; Sourour Zina; Bechir Jelliti; Salim Ben Yahia; Moncef Khairallah
Journal:  Int Ophthalmol       Date:  2016-12-27       Impact factor: 2.031

Review 2.  Molecular biology, pathogenesis and pathology of mumps virus.

Authors:  Steven Rubin; Michael Eckhaus; Linda J Rennick; Connor G G Bamford; W Paul Duprex
Journal:  J Pathol       Date:  2015-01       Impact factor: 7.996

  2 in total

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