BACKGROUND:Deep biliary cannulation is the key for successful endoscopic retrograde cholangiopancreatography (ERCP) procedures. Guidewire-assisted cannulation is associated both with a higher success rate and a reduced risk of post-ERCP pancreatitis compared with standard catheter cannulation. However, to our knowledge there are no prospective, randomized studies comparing the use of different guidewires in biliary cannulation. The goal of this study was to compare the performance of an angled-tipped guidewire (AGW) with a straight-tipped guidewire (SGW) in achieving successful deep biliary cannulation. METHODS:Patients with intended biliary cannulation of an intact papilla were prospectively randomized to angled- or straight-tipped hydrophilic guidewire arms in a tertiary, referral, university hospital setting. Randomized cannulation method was applied either until successful cannulation of the bile duct or until 2 min had passed. Crossover was not included in the study protocol. The main outcome measurements were the cannulation success rate and duration of cannulation. RESULTS: Of the 239 consecutive patients, 155 patients were randomized: in the final analysis 70 patients were included in the AGW arm and 83 patients in the SGW arm. Cannulation time [median; seconds (s)] was shorter with the AGW compared with the SGW (20 vs. 63 s, p = 0.01). There was no difference in the cannulation success rate or the complication rate between the two study groups. CONCLUSIONS: AGW may facilitate biliary cannulation in ERCP.
RCT Entities:
BACKGROUND: Deep biliary cannulation is the key for successful endoscopic retrograde cholangiopancreatography (ERCP) procedures. Guidewire-assisted cannulation is associated both with a higher success rate and a reduced risk of post-ERCP pancreatitis compared with standard catheter cannulation. However, to our knowledge there are no prospective, randomized studies comparing the use of different guidewires in biliary cannulation. The goal of this study was to compare the performance of an angled-tipped guidewire (AGW) with a straight-tipped guidewire (SGW) in achieving successful deep biliary cannulation. METHODS:Patients with intended biliary cannulation of an intact papilla were prospectively randomized to angled- or straight-tipped hydrophilic guidewire arms in a tertiary, referral, university hospital setting. Randomized cannulation method was applied either until successful cannulation of the bile duct or until 2 min had passed. Crossover was not included in the study protocol. The main outcome measurements were the cannulation success rate and duration of cannulation. RESULTS: Of the 239 consecutive patients, 155 patients were randomized: in the final analysis 70 patients were included in the AGW arm and 83 patients in the SGW arm. Cannulation time [median; seconds (s)] was shorter with the AGW compared with the SGW (20 vs. 63 s, p = 0.01). There was no difference in the cannulation success rate or the complication rate between the two study groups. CONCLUSIONS: AGW may facilitate biliary cannulation in ERCP.
Authors: P B Cotton; G Lehman; J Vennes; J E Geenen; R C Russell; W C Meyers; C Liguory; N Nickl Journal: Gastrointest Endosc Date: 1991 May-Jun Impact factor: 9.427
Authors: Juha M Grönroos; Hanna Vihervaara; Risto Gullichsen; Simo Laine; Jukka Karvonen; Paulina Salminen Journal: Surg Endosc Date: 2010-12-07 Impact factor: 4.584
Authors: Hanna Vihervaara; Paulina Salminen; Saija Hurme; Risto Gullichsen; Simo Laine; Juha M Grönroos Journal: Scand J Gastroenterol Date: 2011-09-22 Impact factor: 2.423
Authors: Earl J Williams; Steve Taylor; Peter Fairclough; Adrian Hamlyn; Richard F Logan; Derrick Martin; Stuart A Riley; Peter Veitch; Mark Wilkinson; Paula R Williamson; Martin Lombard Journal: Gut Date: 2006-12-04 Impact factor: 23.059
Authors: Adam A Bailey; Michael J Bourke; Arthur J Kaffes; Karen Byth; Eric Y Lee; Stephen J Williams Journal: Gastrointest Endosc Date: 2009-12-08 Impact factor: 9.427
Authors: P Katsinelos; G Paroutoglou; J Kountouras; G Chatzimavroudis; C Zavos; I Pilpilidis; G Tzelas; G Tzovaras Journal: Endoscopy Date: 2008-02-19 Impact factor: 10.093