BACKGROUND: Tourette syndrome is a combined motor and vocal tic disorder that begins in childhood and takes a chronic course. It arises in about 1% of all children, with highly varying severity. Transient and usually mild tics are seen in as many as 15% of all children in elementary school. The diagnosis is often delayed by several years. METHODS: We selectively reviewed the pertinent literature, including the guidelines of the European Society for the Study of Tourette Syndrome for the diagnosis and treatment of tic disorders. RESULTS: Tic disorders usually take a benign course, with spontaneous improvement in adolescence in about 90% of patients. Psychoeducation is the basis of treatment in each case and almost always brings marked emotional relief. Specific treatment is needed only for more severe tics and those that cause evident psychosocial impairment. 80-90% of patients with Tourette syndrome have comorbidities (attention deficit-hyperactivity disorder, obsessive-compulsive disorder, depression, anxiety, emotional dysregulation, autoaggression), which often impair their quality of life more than the tics do and therefore become the main target of treatment. There is little evidence for the efficacy of treatment for tics. Small-scale controlled studies with a brief follow-up period have been carried out for some neuroleptic drugs. Behavior therapy should be tried before drug treatment. A further option for very severely affected adults is deep brain stimulation. CONCLUSION: Because of the low level of the available evidence, no definitive recommendations can be made for the treatment of tics.
BACKGROUND:Tourette syndrome is a combined motor and vocal tic disorder that begins in childhood and takes a chronic course. It arises in about 1% of all children, with highly varying severity. Transient and usually mild tics are seen in as many as 15% of all children in elementary school. The diagnosis is often delayed by several years. METHODS: We selectively reviewed the pertinent literature, including the guidelines of the European Society for the Study of Tourette Syndrome for the diagnosis and treatment of tic disorders. RESULTS:Tic disorders usually take a benign course, with spontaneous improvement in adolescence in about 90% of patients. Psychoeducation is the basis of treatment in each case and almost always brings marked emotional relief. Specific treatment is needed only for more severe tics and those that cause evident psychosocial impairment. 80-90% of patients with Tourette syndrome have comorbidities (attention deficit-hyperactivity disorder, obsessive-compulsive disorder, depression, anxiety, emotional dysregulation, autoaggression), which often impair their quality of life more than the tics do and therefore become the main target of treatment. There is little evidence for the efficacy of treatment for tics. Small-scale controlled studies with a brief follow-up period have been carried out for some neuroleptic drugs. Behavior therapy should be tried before drug treatment. A further option for very severely affected adults is deep brain stimulation. CONCLUSION: Because of the low level of the available evidence, no definitive recommendations can be made for the treatment of tics.
Authors: Thomas Steeves; B Duncan McKinlay; Daniel Gorman; Lori Billinghurst; Lundy Day; Alan Carroll; Yves Dion; Asif Doja; Sandra Luscombe; Paul Sandor; Tamara Pringsheim Journal: Can J Psychiatry Date: 2012-03 Impact factor: 4.356
Authors: F R Sallee; R Kurlan; C G Goetz; H Singer; L Scahill; G Law; V M Dittman; P B Chappell Journal: J Am Acad Child Adolesc Psychiatry Date: 2000-03 Impact factor: 8.829
Authors: Claudio Da Cunha; Suelen L Boschen; Alexander Gómez-A; Erika K Ross; William S J Gibson; Hoon-Ki Min; Kendall H Lee; Charles D Blaha Journal: Neurosci Biobehav Rev Date: 2015-02-12 Impact factor: 8.989
Authors: Sabrina M Darrow; Cornelia Illmann; Caitlin Gauvin; Lisa Osiecki; Crystelle A Egan; Erica Greenberg; Monika Eckfield; Matthew E Hirschtritt; David L Pauls; James R Batterson; Cheston M Berlin; Irene A Malaty; Douglas W Woods; Jeremiah M Scharf; Carol A Mathews Journal: Psychiatry Res Date: 2015-05-27 Impact factor: 3.222