Literature DB >> 23248374

Authors' reply.

Thirthar Palanivelu Vetrichevvel1, Rangarajan Sudha, Subramanyam Shobana, Sankarasubramanian Anandan.   

Abstract

Entities:  

Year:  2012        PMID: 23248374      PMCID: PMC3519263          DOI: 10.4103/0019-5154.103076

Source DB:  PubMed          Journal:  Indian J Dermatol        ISSN: 0019-5154            Impact factor:   1.494


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Sir, We thank the authors for their interest in our article, “Zosteriform fixed drug eruption to Levofloxacin”.[1] Our patient had presented with fixed drug eruption (FDE) associated with multiple fluid filled lesions on the lateral trunk, a clinical picture reminisce of herpes zoster. However, we have expressed our limitations on a dermatomal cause as “inexplicable” and highlighted this unique presentation of FDE due to Levofloxacin. In our attempt to identify the cause of this unique presentation, we had presented to the readers, an exhaustive list of possible causes including viscero-cutaneous reflex zones and negated them based on history and examination. We would like to underline the fact that, in our discussion on the possibility of linear and disseminated drug eruption, we had also mentioned the concept of heterozygosity and homozygosity that forms the genetic basis that could explain the clinical appearance of these lesions and have duly referenced Happle et al.'s article on co-existing linear and disseminated drug eruption. However, we acknowledge the author's contribution in emphasizing and explaining the paradigm.
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1.  Zosteriform fixed drug eruption to levofloxacin.

Authors:  T P Vetrichevvel; R Sudha; S Shobana; S Anandan
Journal:  Indian J Dermatol       Date:  2012-07       Impact factor: 1.494

  1 in total

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