OBJECTIVES: To evaluate the effects of particles and their components on lung function. METHODS: A panel study was conducted on 107 primary schoolchildren. The peak expiratory flow rate (PEFR) for each subject was measured three times a day for 40 days continuously. Particulate air concentrations were measured every day. The concentrations of Pb, Ni, Fe, Mn, Cr, As, Cd, and Zn in particles were measured. Linear mixed-effect models were used to estimate the associations between particles, metal elements, and PEFR. RESULTS: We found that the increase in particles in air was associated with a significant reduction in PEFR. Its effects lasted 2 to 5 days. Pb, Ni, Fe, Mn, and Cr in particles also reduced PEFR. As and Cd increased PEFR. Zn showed inconstant effects on PEFR. CONCLUSION: This study suggested that most metal components in particles have negative effects on children's lung function.
OBJECTIVES: To evaluate the effects of particles and their components on lung function. METHODS: A panel study was conducted on 107 primary schoolchildren. The peak expiratory flow rate (PEFR) for each subject was measured three times a day for 40 days continuously. Particulate air concentrations were measured every day. The concentrations of Pb, Ni, Fe, Mn, Cr, As, Cd, and Zn in particles were measured. Linear mixed-effect models were used to estimate the associations between particles, metal elements, and PEFR. RESULTS: We found that the increase in particles in air was associated with a significant reduction in PEFR. Its effects lasted 2 to 5 days. Pb, Ni, Fe, Mn, and Cr in particles also reduced PEFR. As and Cd increased PEFR. Zn showed inconstant effects on PEFR. CONCLUSION: This study suggested that most metal components in particles have negative effects on children's lung function.
Authors: Maria José Rosa; Marcela Tamayo-Ortiz; Adriana Mercado Garcia; Nadya Y Rivera Rivera; Douglas Bush; Alison G Lee; Maritsa Solano-González; Chitra Amarasiriwardena; Martha Maria Téllez-Rojo; Robert O Wright; Rosalind J Wright Journal: Environ Res Date: 2021-12-05 Impact factor: 6.498