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Literature DB >> 23244761

Shaping the p53 response with nucleoporins.

Melanie L Yarbrough¹, Michael A White, Beatriz M A Fontoura.

Abstract

In this issue, Singer et al. (2012) reveal that the nucleoporin Nup98 supports adaptation to genotoxic stress by protecting specific p53-induced mRNAs from exosome-dependent degradation, suggesting that wild-type Nup98 may possess tumor suppressor function.

Entities: Disease Gene Species

Year: 2012 PMID： 23244761 PMCID： PMC3597242 DOI： 10.1016/j.molcel.2012.11.027

Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970

10 in total

1. Role of nucleoporin induction in releasing an mRNA nuclear export block.

Authors: Jost Enninga; David E Levy; Günter Blobel; Beatriz M A Fontoura
Journal: Science Date: 2002-01-24 Impact factor: 47.728

Review 2. Gene positioning and expression.

Authors: Defne Egecioglu; Jason H Brickner
Journal: Curr Opin Cell Biol Date: 2011-02-01 Impact factor: 8.382

3. Nup98 is a mobile nucleoporin with transcription-dependent dynamics.

Authors: Eric R Griffis; Nihal Altan; Jennifer Lippincott-Schwartz; Maureen A Powers
Journal: Mol Biol Cell Date: 2002-04 Impact factor: 4.138

4. The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

Authors: Karthik B Jeganathan; Liviu Malureanu; Jan M van Deursen
Journal: Nature Date: 2005-12-15 Impact factor: 49.962

5. The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways.

Authors: M A Powers; D J Forbes; J E Dahlberg; E Lund
Journal: J Cell Biol Date: 1997-01-27 Impact factor: 10.539

Review 6. Nuclear pore proteins and cancer.

Authors: Songli Xu; Maureen A Powers
Journal: Semin Cell Dev Biol Date: 2009-03-18 Impact factor: 7.727

7. Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.

Authors: Stephan Singer; Ruiying Zhao; Anthony M Barsotti; Anette Ouwehand; Mina Fazollahi; Elias Coutavas; Kai Breuhahn; Olaf Neumann; Thomas Longerich; Tobias Pusterla; Maureen A Powers; Keith M Giles; Peter J Leedman; Jochen Hess; David Grunwald; Harmen J Bussemaker; Robert H Singer; Peter Schirmacher; Carol Prives
Journal: Mol Cell Date: 2012-10-24 Impact factor: 17.970

8. The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation.

Authors: Timothy A Bolger; Andrew W Folkmann; Elizabeth J Tran; Susan R Wente
Journal: Cell Date: 2008-08-22 Impact factor: 41.582

9. Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK.

Authors: Marie K Cross; Maureen A Powers
Journal: Mol Biol Cell Date: 2011-01-05 Impact factor: 4.138

10. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.

Authors: Gang G Wang; Jikui Song; Zhanxin Wang; Holger L Dormann; Fabio Casadio; Haitao Li; Jun-Li Luo; Dinshaw J Patel; C David Allis
Journal: Nature Date: 2009-06-11 Impact factor: 49.962

10 in total

3 in total

Review 1. Nuclear trafficking in health and disease.

Authors: Amir Mor; Michael A White; Beatriz M A Fontoura
Journal: Curr Opin Cell Biol Date: 2014-02-11 Impact factor: 8.382

2. Bridge-Induced Translocation between NUP145 and TOP2 Yeast Genes Models the Genetic Fusion between the Human Orthologs Associated With Acute Myeloid Leukemia.

Authors: Valentina Tosato; Nicole West; Jan Zrimec; Dmitri V Nikitin; Giannino Del Sal; Roberto Marano; Michael Breitenbach; Carlo V Bruschi
Journal: Front Oncol Date: 2017-09-29 Impact factor: 6.244

Review 3. Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export.

Authors: Sharon K Kuss; Miguel A Mata; Liang Zhang; Beatriz M A Fontoura
Journal: Viruses Date: 2013-07-18 Impact factor: 5.048

3 in total