OBJECTIVE: To observe efficacy and side effects, as well as the impact on quality of life, of Kanglaite® (Coix Seed Oil) injections combined with chemotherapy in the treatment of advanced gastric cancer patiensts. METHOD:A consecutive cohort of 60 patients were divided into two groups:the experimental group receiving Kanglaite® Injection combined with chemotherapy and the control group with chemotherapy alone. After more than two courses of treatment, efficacy, quality of life and side effects were evaluated. RESULTS: The response rate and KPS score of experimental group were significantly improved as compared with those of the control group(P<0.05). In addition, gastrointestinal reactions and bone marrow suppression were significantly lower than in the control group(P<0.05). CONCLUSIONS:Kanglaite® Injection enhanced efficacy and reduced the side effects of chemotherapy, improving quality of life of gastric cancer patients; use of Kanglaite® injections deserves to be further investigated in randomized control clinical trails.
RCT Entities:
OBJECTIVE: To observe efficacy and side effects, as well as the impact on quality of life, of Kanglaite® (Coix Seed Oil) injections combined with chemotherapy in the treatment of advanced gastric cancer patiensts. METHOD: A consecutive cohort of 60 patients were divided into two groups:the experimental group receiving Kanglaite® Injection combined with chemotherapy and the control group with chemotherapy alone. After more than two courses of treatment, efficacy, quality of life and side effects were evaluated. RESULTS: The response rate and KPS score of experimental group were significantly improved as compared with those of the control group(P<0.05). In addition, gastrointestinal reactions and bone marrow suppression were significantly lower than in the control group(P<0.05). CONCLUSIONS: Kanglaite® Injection enhanced efficacy and reduced the side effects of chemotherapy, improving quality of life of gastric cancerpatients; use of Kanglaite® injections deserves to be further investigated in randomized control clinical trails.
Authors: Zhidong Wang; Jun Li; Yuanyuan Ji; Peng An; Shu Zhang; Zongfang Li Journal: Evid Based Complement Alternat Med Date: 2013-07-11 Impact factor: 2.629
Authors: Lee S Schwartzberg; Francis P Arena; Bryan J Bienvenu; Edward H Kaplan; Luis H Camacho; Luis T Campos; J Paul Waymack; Mary A Tagliaferri; Michael M Chen; Dapeng Li Journal: J Cancer Date: 2017-07-03 Impact factor: 4.207