Literature DB >> 23243154

MDS: unraveling the mystery.

David A Rizzieri1.   

Abstract

In this issue of Blood, Sekeres et al report a phase 2 study of lenalidomide and azacitidine for higher risk myelodysplastic syndromes (MDS). High overall response and duration of response supports the concept of combination, multitargeted approaches rather than traditional chemotherapeutics for this disease.

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Year:  2012        PMID: 23243154     DOI: 10.1182/blood-2012-09-452755

Source DB:  PubMed          Journal:  Blood        ISSN: 0006-4971            Impact factor:   22.113


  1 in total

1.  Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability.

Authors:  Fabio Giuseppe Liberante; Katrina Lappin; Eliana M Barros; Jekaterina Vohhodina; Florian Grebien; Kienan I Savage; Kenneth Ian Mills
Journal:  Sci Rep       Date:  2019-02-25       Impact factor: 4.379

  1 in total

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