Literature DB >> 23242086

Coexistent metastatic melanoma of the kidney with unknown primary and renal cell carcinoma.

Maulik Dhandha1, Melinda B Chu, John M Richart.   

Abstract

In this report, we present an African-American female patient who presented with haematuria to her primary care physician. The symptoms persisted and coexistent metastatic spindle cell-type melanoma of the kidney and renal cell carcinoma were discovered on further evaluation. No primary site for melanoma was identified. Despite aggressive treatment with ipilimumab, the patient's disease progressed quickly. The patient opted for palliative care and was referred to a hospice. Coexistent melanoma and renal cell carcinoma is exceedingly rare. Melanoma itself is rare in the African-American population. However, when it does present, it usually is at an advanced stage, as was the case in our patient. Since no primary tumour site for melanoma was found and the diagnosis was made after the tumour had metastasised, we think this case highlights the importance of cutaneous cancer surveillance in the non-Caucasian population. Earlier identification of melanoma in this population will help to improve outcomes.

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Year:  2012        PMID: 23242086      PMCID: PMC4544279          DOI: 10.1136/bcr-2012-007286

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

1.  Increased risk of second primary cancers after a diagnosis of melanoma.

Authors:  Porcia T Bradford; D Michal Freedman; Alisa M Goldstein; Margaret A Tucker
Journal:  Arch Dermatol       Date:  2010-03

Review 2.  Coexistent B-cell lymphoma and cutaneous T-cell lymphoma.

Authors:  Taku Inokuchi; Mayumi Shincho; Yuji Moriwaki; Tsuneyoshi Ka; Sumio Takahashi; Zenta Tsutsumi; Yoshiaki Lin; Seiichi Hirota; Tetsuya Yamamoto
Journal:  Intern Med       Date:  2006-06-01       Impact factor: 1.271

3.  Second primary tumors in patients with cutaneous malignant melanoma.

Authors:  S Bhatia; L Estrada-Batres; T Maryon; M Bogue; D Chu
Journal:  Cancer       Date:  1999-11-15       Impact factor: 6.860

4.  Characteristics of the coexistence of melanoma and renal cell carcinoma.

Authors:  Eve Maubec; Valérie Chaudru; Hamida Mohamdi; Florent Grange; Jean-Jacques Patard; Stéphane Dalle; Béatrice Crickx; Brigitte Bressac-de Paillerets; Florence Demenais; Marie-Françoise Avril
Journal:  Cancer       Date:  2010-12-15       Impact factor: 6.860

5.  Second primary cancers in patients with cutaneous malignant melanoma: a population-based study in Sweden.

Authors:  C Wassberg; M Thörn; J Yuen; U Ringborg; T Hakulinen
Journal:  Br J Cancer       Date:  1996-01       Impact factor: 7.640

  5 in total

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