Literature DB >> 23242031

New 2,3-diaminopropionic acid inhibitors of AGE and ALE formation.

Nicolas Audic1, Guy Potier, N André Sasaki.   

Abstract

Novel 2,3-diaminopropionic acid-based molecules were synthesised and tested successfully as glyoxal/methylglyoxal scavengers and as AGE inhibitors. Addition of an 8-hydroxyquinoline moiety led to an increase of the overall activity. The compounds tested in this study were also proved to be efficient in trapping ALE precursor malondialdehyde.

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Year:  2012        PMID： 23242031     DOI： 10.1039/c2ob27084f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  L-2,3-diaminopropionate generates diverse metabolic stresses in Salmonella enterica.

Authors:  Dustin C Ernst; Mary E Anderson; Diana M Downs
Journal:  Mol Microbiol       Date:  2016-05-06       Impact factor: 3.501

2.  Design and Synthesis of Nanosensor Based on CdSe Quantum Dots Functionalized with 8-Hydroxyquinoline: a Fluorescent Sensor for Detection of Al3+ in Aqueous Solution.

Authors:  Bagher Eftekhari-Sis; Khadijeh Samadneshan; Saleh Vahdati-Khajeh
Journal:  J Fluoresc       Date:  2018-05-28       Impact factor: 2.217

3.  2,3-Diaminopropanols Obtained from d-Serine as Intermediates in the Synthesis of Protected 2,3-l-Diaminopropanoic Acid (l-Dap) Methyl Esters.

Authors:  Andrea Temperini; Donatella Aiello; Fabio Mazzotti; Constantinos M Athanassopoulos; Pierantonio De Luca; Carlo Siciliano
Journal:  Molecules       Date:  2020-03-13       Impact factor: 4.411
  3 in total

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