Dementia and neuroimaging.

Early diagnosis of dementing conditions and an accurate monitoring of their progression are important clinical and research goals, especially given the improving prospects of disease-modifying therapies. Neuroimaging has played and is playing an important role in detecting reversible, treatable causes of dementia, and in characterizing the dementia syndromes by demonstrating structural and functional signatures that can aid in their differentiation. Many new imaging techniques and modalities are also available that allow the assessment of specific aspects of brain structure and function, such as positron emission tomography with new ligands, diffusion tensor magnetic resonance imaging (MRI) and functional MRI. In this review, we report the most recent findings from the papers published in the Journal of Neurology that used conventional and advanced neuroimaging techniques for the study of various dementing conditions.