Literature DB >> 23241827

Surgical intervention of steroid-induced ocular hypertension from Ozurdex.

Poonam Sejpal1, Joni Scott-Weideman.   

Abstract

PURPOSE: To present a case study on the management of ocular hypertension induced by repeated Ozurdex implants. CASE REPORT: A 51-year-old white man presented to the Tallahassee Veterans Affairs Outpatient Clinic as requested by the retinal specialist for an intraocular pressure (IOP) check. Two months before this visit, the patient was given an Ozurdex implant in each eye for reoccurring diabetic macular edema. Subsequent follow-up examinations documented the intervals between repeated Ozurdex implants and the increase in IOP, with progression to surgical intervention to control eye pressures.
CONCLUSIONS: Results from previous studies and this case report indicate that maximum IOP occurs at approximately 8 weeks after injection of an Ozurdex implant. Although most patients can be managed by IOP-lowering medications, this case is unique because it is an example of repeated implants at approximately 4-month intervals that led to surgical intervention to control IOP. Evidence-based knowledge of Ozurdex as reviewed in this article will lead to better patient postoperative management.

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Year:  2013        PMID: 23241827     DOI: 10.1097/OPX.0b013e318279eba0

Source DB:  PubMed          Journal:  Optom Vis Sci        ISSN: 1040-5488            Impact factor:   1.973


  1 in total

1.  Statistical design for formulation optimization of hydrocortisone butyrate-loaded PLGA nanoparticles.

Authors:  Xiaoyan Yang; Sulabh Patel; Ye Sheng; Dhananjay Pal; Ashim K Mitra
Journal:  AAPS PharmSciTech       Date:  2014-02-07       Impact factor: 3.246

  1 in total

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