Literature DB >> 2324058

A family history study of neuropsychiatric disorders in the adult siblings of autistic individuals.

J Piven1, J Gayle, G A Chase, B Fink, R Landa, M M Wzorek, S E Folstein.   

Abstract

The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) had received treatment for affective disorder. This study is the first to investigate the frequency of disorders in the adult siblings of autistic probands. These results suggest aggregation of a variety of neuropsychiatric disorders in the siblings of autistic individuals.

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Year:  1990        PMID： 2324058     DOI： 10.1097/00004583-199003000-00004

Source DB:  PubMed          Journal:  J Am Acad Child Adolesc Psychiatry        ISSN： 0890-8567            Impact factor:   8.829


  43 in total

Review 1.  Genetic studies of autism: from the 1970s into the millennium.

Authors:  M Rutter
Journal:  J Abnorm Child Psychol       Date:  2000-02

2.  Childhood autism: its diagnosis, nature, and treatment.

Authors:  S Wolff
Journal:  Arch Dis Child       Date:  1991-06       Impact factor: 3.791

Review 3.  The screening and diagnosis of autistic spectrum disorders.

Authors:  P A Filipek; P J Accardo; G T Baranek; E H Cook; G Dawson; B Gordon; J S Gravel; C P Johnson; R J Kallen; S E Levy; N J Minshew; S Ozonoff; B M Prizant; I Rapin; S J Rogers; W L Stone; S Teplin; R F Tuchman; F R Volkmar
Journal:  J Autism Dev Disord       Date:  1999-12

4.  Neuropsychological functioning of siblings of children with autism, siblings of children with developmental language delay, and siblings of children with mental retardation of unknown genetic etiology.

Authors:  Tammy Pilowsky; Nurit Yirmiya; Varda Gross-Tsur; Ruth S Shalev
Journal:  J Autism Dev Disord       Date:  2007-03

5.  The development of young siblings of children with autism from 4 to 54 months.

Authors:  Ifat Gamliel; Nurit Yirmiya; Marian Sigman
Journal:  J Autism Dev Disord       Date:  2007-01-03

6.  Defining key features of the broad autism phenotype: a comparison across parents of multiple- and single-incidence autism families.

Authors:  Molly Losh; Debra Childress; Kristen Lam; Joseph Piven
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2008-06-05       Impact factor: 3.568

7.  Depression in children with autism/pervasive developmental disorders: a case-control family history study.

Authors:  M Ghaziuddin; J Greden
Journal:  J Autism Dev Disord       Date:  1998-04

8.  Autism in tuberous sclerosis complex.

Authors:  G C Gutierrez; S L Smalley; P E Tanguay
Journal:  J Autism Dev Disord       Date:  1998-04

Review 9.  Nosological and genetic aspects of Asperger syndrome.

Authors:  F R Volkmar; A Klin; D Pauls
Journal:  J Autism Dev Disord       Date:  1998-10

10.  Parental attributions for the behavior problems of children and adolescents with autism spectrum disorders.

Authors:  Sigan L Hartley; Emily M Schaidle; Cynthia F Burnson
Journal:  J Dev Behav Pediatr       Date:  2013 Nov-Dec       Impact factor: 2.225
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