Literature DB >> 2323775

Chromosomal in situ hybridization of a Hodgkin's disease-derived cell line (L540) using DNA probes for TCRA, TCRB, MET, and rRNA.

C Fonatsch1, G Gradl, U Kolbus, H Rieder, H Tesch.   

Abstract

The Hodgkin's lymphoma-derived cell line L540, which exhibits multiple marker chromosomes and a genotype characteristic of T-cell origin, showed expression of MET oncogene. L540 was studied by in situ hybridization for chromosomal rearrangements concerning the regions where genes for TCRA and TCRB chains, for MET oncogene, and for rRNA are located. All four genes were demonstrated to be involved in the formation of marker chromosomes. Especially remarkable was the participation of rDNA-bearing regions in two different translocations.

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Year:  1990        PMID： 2323775     DOI： 10.1007/bf00195814

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  26 in total

1.  Fused transcript of abl and bcr genes in chronic myelogenous leukaemia.

Authors:  E Shtivelman; B Lifshitz; R P Gale; E Canaani
Journal:  Nature       Date:  1985 Jun 13-19       Impact factor: 49.962

2.  Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc.

Authors:  B Henglein; H Synovzik; P Groitl; G W Bornkamm; P Hartl; M Lipp
Journal:  Mol Cell Biol       Date:  1989-05       Impact factor: 4.272

3.  Secondary activation of c-abl may be related to translocation to the nucleolar organizer region in an in vitro cultured rat leukemia cell line (K3D).

Authors:  R Takahashi; K Mihara; S Maeda; T Yamaguchi; H L Chen; N Aoyama; S Murao; M Hatanaka; T Sugiyama
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

4.  Human gene mapping 9.5. Update to the Ninth International Workshop on Human Gene Mapping. New Haven Conference, August 1988.

Authors: 
Journal:  Cytogenet Cell Genet       Date:  1988

5.  Chromosomal localization of the human T cell receptor beta-chain genes.

Authors:  M M Le Beau; M O Diaz; J D Rowley; T W Mak
Journal:  Cell       Date:  1985-05       Impact factor: 41.582

6.  Molecular cloning of a new transforming gene from a chemically transformed human cell line.

Authors:  C S Cooper; M Park; D G Blair; M A Tainsky; K Huebner; C M Croce; G F Vande Woude
Journal:  Nature       Date:  1984 Sep 6-11       Impact factor: 49.962

7.  Ectopic nucleolus organizer regions (NORs) in human testicular tumors.

Authors:  C D DeLozier-Blanchet; H Walt; E Engel
Journal:  Cytogenet Cell Genet       Date:  1986

8.  Cytochemical, immunologic, chromosomal, and molecular genetic analysis of a novel cell line derived from Hodgkin's disease.

Authors:  H Kamesaki; S Fukuhara; E Tatsumi; H Uchino; H Yamabe; H Miwa; S Shirakawa; M Hatanaka; T Honjo
Journal:  Blood       Date:  1986-07       Impact factor: 22.113

9.  Molecular analysis of Hodgkin's disease-derived cell lines.

Authors:  H Tesch; M Jücker; M H Falk; G W Bornkamm; D B Jones; V Diehl
Journal:  Hematol Oncol       Date:  1988 Jul-Sep       Impact factor: 5.271

10.  Rearrangements of chromosomal regions containing ribosomal RNA genes and centromeric heterochromatin in the human melanoma cell line MeWo.

Authors:  J J Holden; D L Reimer; J C Roder; B N White
Journal:  Cancer Genet Cytogenet       Date:  1986-04-01
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