Literature DB >> 2323535

Characteristic new members of the phthiocerol and phenolphthiocerol families from Mycobacterium ulcerans.

G S Besra1, D E Minnikin, A Sharif, J L Stanford.   

Abstract

Diacyl phthiodiolone A and phenolphthiodiolone A lipids were isolated from two strains of Mycobacterium ulcerans. The diol units of the phthiodiolone A and phenolphthiodiolone A components were shown to have erythro stereochemistry by infrared spectroscopy and proton nuclear magnetic resonance of an acetal derivative. This stereochemistry is shared only by related diols from M. marinum, the diols from M. bovis, M. kansasii, M. leprae and M. tuberculosis having threo stereochemistry.

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Year:  1990        PMID： 2323535     DOI： 10.1016/0378-1097(90)90250-t

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  3 in total

1.  Identification of phthiodiolone ketoreductase, an enzyme required for production of mycobacterial diacyl phthiocerol virulence factors.

Authors:  Kenolisa C Onwueme; Cheryl J Vos; Juan Zurita; Clifford E Soll; Luis E N Quadri
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

2.  Mycobacterial polyketide-associated proteins are acyltransferases: proof of principle with Mycobacterium tuberculosis PapA5.

Authors:  Kenolisa C Onwueme; Julian A Ferreras; John Buglino; Christopher D Lima; Luis E N Quadri
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-18       Impact factor: 11.205

Review 3.  The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system.

Authors:  Sarah M Batt; David E Minnikin; Gurdyal S Besra
Journal:  Biochem J       Date:  2020-05-29       Impact factor: 3.857
  3 in total

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