| Literature DB >> 23234407 |
To Dao Cuong1, Tran Manh Hung, Jin Cheol Kim, Eun Hee Kim, Mi Hee Woo, Jae Sue Choi, Jeong Hyung Lee, Byung Sun Min.
Abstract
Four new phenolic compounds, caesalpiniaphenols A-D (1-4), together with eight known compounds were isolated from Caesalpinia sappan heartwood. The chemical structures were established mainly by NMR, MS, ECD, and Mosher's method. Compounds 4, 5, and 7 showed weak inhibitory activity against the LPS-induced NO production in macrophage RAW264.7 cells with IC(50) values of 12.2, 3.5, and 5.7 μM, respectively.Entities:
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Year: 2012 PMID： 23234407 DOI： 10.1021/np3003673
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050