Literature DB >> 23233249

The role of needle biopsy for focal bone lesions with complete fluid-fluid levels on magnetic resonance imaging.

G Rajeswaran1, Q Malik, A Saifuddin.   

Abstract

OBJECTIVE: To assess the value of image-guided needle biopsy of bone lesions completely filled with fluid-fluid levels (FFLs) on magnetic resonance imaging (MRI) and the safety of primary surgical curettage.
MATERIALS AND METHODS: The radiology database was searched for all reports containing "fluid level" from 1998 to 2011 and the imaging was reviewed retrospectively. Inclusion criteria were patients with bone lesions completely filled with FFLs on MRI (defined as FFLs on every axial and/or sagittal T2-weighted or Short Tau Inversion Recovery (STIR) sequence). The pathology database was then reviewed for the outcome of needle biopsy (n=14) and for the outcome of surgical curettage, either post-biopsy or primary (n=52).
RESULTS: There were 53 patients (mean age 18 years; M=34, F=19). Fourteen patients underwent percutaneous needle biopsy, which was diagnostic in five (36 %) and non-diagnostic in nine (64 %). Fifty-two patients had surgical curettage/resection, which was diagnostic in 50 (96 %) and non-diagnostic in two (4 %). All lesions were benign; 78 % were aneurysmal bone cysts (ABC), 8 % were lesions with ABC change, and 14 % were simple bone cysts.
CONCLUSIONS: Our results suggest that patients with bone lesions completely filled with FFLs on MRI are almost certain to be benign, provided that the clinical and radiological features are not atypical. Percutaneous needle biopsy in such cases is unlikely to be of value and these lesions can be safely managed with primary surgical curettage.

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Year:  2012        PMID: 23233249     DOI: 10.1007/s00256-012-1542-y

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  15 in total

1.  Plasmacytoma of the sacrum: fluid-fluid levels on MR images.

Authors:  S B Harter; S R Nokes
Journal:  AJR Am J Roentgenol       Date:  1995-09       Impact factor: 3.959

Review 2.  Fluid-fluid levels in a simple bone cyst on magnetic resonance imaging.

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Journal:  Australas Radiol       Date:  1998-08

3.  Fluid-fluid level in an intraosseous ganglion.

Authors:  A C Grey; D C Mangham; A M Davies; R J Grimer
Journal:  Skeletal Radiol       Date:  1997-11       Impact factor: 2.199

Review 4.  Giant-cell tumor of the tibia in a child presenting as an expansile metaphyseal lesion with fluid-fluid levels on MR.

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Journal:  Magn Reson Imaging       Date:  1990       Impact factor: 2.546

5.  Fluid-fluid level: a nonspecific finding in tumors of bone and soft tissue.

Authors:  J C Tsai; M K Dalinka; M D Fallon; M B Zlatkin; H Y Kressel
Journal:  Radiology       Date:  1990-06       Impact factor: 11.105

6.  Prevalence, extension and characteristics of fluid-fluid levels in bone and soft tissue tumors.

Authors:  P Van Dyck; F M Vanhoenacker; J Vogel; C Venstermans; H M Kroon; J Gielen; P M Parizel; J L Bloem; A M A De Schepper
Journal:  Eur Radiol       Date:  2006-04-13       Impact factor: 5.315

7.  The prevalence and diagnostic significance of fluid-fluid levels in focal lesions of bone.

Authors:  P O'Donnell; A Saifuddin
Journal:  Skeletal Radiol       Date:  2004-05-06       Impact factor: 2.199

8.  [Fluid-fluid levels in bone and soft tissue tumors demonstrated by MR imaging].

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Journal:  Nihon Igaku Hoshasen Gakkai Zasshi       Date:  1992-08-25

9.  MR imaging of a malignant schwannoma and an osteoblastoma with fluid-fluid levels. Report of two new cases.

Authors:  J C Vilanova; J L Dolz; J L Maestro de Leon; A Aparicio; J Aldomà; A Capdevila
Journal:  Eur Radiol       Date:  1998       Impact factor: 5.315

10.  Prevalence and diagnostic significance of fluid-fluid levels in soft-tissue neoplasms.

Authors:  F Alyas; J Lee; M Ahmed; D Connell; A Saifuddin
Journal:  Clin Radiol       Date:  2007-05-11       Impact factor: 2.350

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  3 in total

1.  Computer-aided resection and reconstruction in a case of aneurysmal bone cyst of the mandibular condylar head.

Authors:  Wenko Smolka; Ullrich Müller-Lisse; Karl Sotlar; Carl-Peter Cornelius
Journal:  Oral Maxillofac Surg       Date:  2015-07-02

Review 2.  The role of MRI in image-guided needle biopsy of focal bone and soft tissue neoplasms.

Authors:  M M Y Khoo; A Saifuddin
Journal:  Skeletal Radiol       Date:  2013-05-04       Impact factor: 2.199

3.  Paediatric bone lesions: diagnostic accuracy of imaging correlation and CT-guided needle biopsy for differentiating benign from malignant lesions.

Authors:  Alessandro Vidoni; Ian Pressney; Asif Saifuddin
Journal:  Br J Radiol       Date:  2021-02-10       Impact factor: 3.039

  3 in total

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