Literature DB >> 23232986

The rationale for initiating treatment of hypercholesterolemia in young adulthood.

Daniel Steinberg1.   

Abstract

Even though it has been recognized for some time that the lesions of atherosclerosis begin in childhood, there has been reluctance to recommend intervention, especially intervention with drugs, before the age of 50 years. Recent evidence, particularly evidence from human genetics, has greatly strengthened the case for earlier intervention to correct hypercholesterolemia and other risk factors. This report briefly reviews some of the emerging lines of evidence that are helping us reach a consensus on when and how we should intervene.

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Year:  2013        PMID： 23232986     DOI： 10.1007/s11883-012-0296-2

Source DB:  PubMed          Journal:  Curr Atheroscler Rep        ISSN： 1523-3804            Impact factor:   5.113


  33 in total

1.  Coronary disease among United States soldiers killed in action in Korea; preliminary report.

Authors:  W F ENOS; R H HOLMES; J BEYER
Journal:  J Am Med Assoc       Date:  1953-07-18

2.  Should age and time be eliminated from cardiovascular risk prediction models? Rationale for the creation of a new national risk detection program.

Authors:  Paul M Ridker; Nancy Cook
Journal:  Circulation       Date:  2005-02-08       Impact factor: 29.690

3.  Statin treatment in children with familial hypercholesterolemia: the younger, the better.

Authors:  Jessica Rodenburg; Maud N Vissers; Albert Wiegman; A S Paul van Trotsenburg; Anouk van der Graaf; Eric de Groot; Frits A Wijburg; John J P Kastelein; Barbara A Hutten
Journal:  Circulation       Date:  2007-07-30       Impact factor: 29.690

Review 4.  A receptor-mediated pathway for cholesterol homeostasis.

Authors:  M S Brown; J L Goldstein
Journal:  Science       Date:  1986-04-04       Impact factor: 47.728

5.  Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.

Authors:  Marianne Abifadel; Mathilde Varret; Jean-Pierre Rabès; Delphine Allard; Khadija Ouguerram; Martine Devillers; Corinne Cruaud; Suzanne Benjannet; Louise Wickham; Danièle Erlich; Aurélie Derré; Ludovic Villéger; Michel Farnier; Isabel Beucler; Eric Bruckert; Jean Chambaz; Bernard Chanu; Jean-Michel Lecerf; Gerald Luc; Philippe Moulin; Jean Weissenbach; Annick Prat; Michel Krempf; Claudine Junien; Nabil G Seidah; Catherine Boileau
Journal:  Nat Genet       Date:  2003-06       Impact factor: 38.330

6.  Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial.

Authors:  Albert Wiegman; Barbara A Hutten; Eric de Groot; Jessica Rodenburg; Henk D Bakker; Harry R Büller; Eric J G Sijbrands; John J P Kastelein
Journal:  JAMA       Date:  2004-07-21       Impact factor: 56.272

7.  Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study.

Authors:  G S Berenson; S R Srinivasan; W Bao; W P Newman; R E Tracy; W A Wattigney
Journal:  N Engl J Med       Date:  1998-06-04       Impact factor: 91.245

Review 8.  Natural history and risk factors for early human atherogenesis. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group.

Authors:  J P Strong
Journal:  Clin Chem       Date:  1995-01       Impact factor: 8.327

9.  Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.

Authors:  Sekar Kathiresan; Olle Melander; Candace Guiducci; Aarti Surti; Noël P Burtt; Mark J Rieder; Gregory M Cooper; Charlotta Roos; Benjamin F Voight; Aki S Havulinna; Björn Wahlstrand; Thomas Hedner; Dolores Corella; E Shyong Tai; Jose M Ordovas; Göran Berglund; Erkki Vartiainen; Pekka Jousilahti; Bo Hedblad; Marja-Riitta Taskinen; Christopher Newton-Cheh; Veikko Salomaa; Leena Peltonen; Leif Groop; David M Altshuler; Marju Orho-Melander
Journal:  Nat Genet       Date:  2008-01-13       Impact factor: 38.330

10.  Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

Authors:  Cristen J Willer; Serena Sanna; Anne U Jackson; Angelo Scuteri; Lori L Bonnycastle; Robert Clarke; Simon C Heath; Nicholas J Timpson; Samer S Najjar; Heather M Stringham; James Strait; William L Duren; Andrea Maschio; Fabio Busonero; Antonella Mulas; Giuseppe Albai; Amy J Swift; Mario A Morken; Narisu Narisu; Derrick Bennett; Sarah Parish; Haiqing Shen; Pilar Galan; Pierre Meneton; Serge Hercberg; Diana Zelenika; Wei-Min Chen; Yun Li; Laura J Scott; Paul A Scheet; Jouko Sundvall; Richard M Watanabe; Ramaiah Nagaraja; Shah Ebrahim; Debbie A Lawlor; Yoav Ben-Shlomo; George Davey-Smith; Alan R Shuldiner; Rory Collins; Richard N Bergman; Manuela Uda; Jaakko Tuomilehto; Antonio Cao; Francis S Collins; Edward Lakatta; G Mark Lathrop; Michael Boehnke; David Schlessinger; Karen L Mohlke; Gonçalo R Abecasis
Journal:  Nat Genet       Date:  2008-01-13       Impact factor: 38.330
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  5 in total

Review 1.  Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.

Authors:  Albert Wiegman; Samuel S Gidding; Gerald F Watts; M John Chapman; Henry N Ginsberg; Marina Cuchel; Leiv Ose; Maurizio Averna; Catherine Boileau; Jan Borén; Eric Bruckert; Alberico L Catapano; Joep C Defesche; Olivier S Descamps; Robert A Hegele; G Kees Hovingh; Steve E Humphries; Petri T Kovanen; Jan Albert Kuivenhoven; Luis Masana; Børge G Nordestgaard; Päivi Pajukanta; Klaus G Parhofer; Frederick J Raal; Kausik K Ray; Raul D Santos; Anton F H Stalenhoef; Elisabeth Steinhagen-Thiessen; Erik S Stroes; Marja-Riitta Taskinen; Anne Tybjærg-Hansen; Olov Wiklund
Journal:  Eur Heart J       Date:  2015-05-25       Impact factor: 29.983

2.  American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease.

Authors:  Natalie R Hasbani; Symen Ligthart; Michael R Brown; Adam S Heath; Allison Bebo; Kellan E Ashley; Eric Boerwinkle; Alanna C Morrison; Aaron R Folsom; David Aguilar; Paul S de Vries
Journal:  Circulation       Date:  2022-01-31       Impact factor: 29.690

3.  Nutritional Treatment in a Cohort of Pediatric Patients with Familial Hypercholesterolaemia: Effect on Lipid Profile.

Authors:  Maria Elena Capra; Cristina Pederiva; Claudia Viggiano; Enrico Fabrizi; Giuseppe Banderali; Giacomo Biasucci
Journal:  Nutrients       Date:  2022-07-08       Impact factor: 6.706

Review 4.  Should We Be Screening for Ischaemic Heart Disease Earlier in Childhood?

Authors:  Pier Paolo Bassareo; Stephen T O'Brien; Esme Dunne; Sophie Duignan; Eliana Martino; Francesco Martino; Colin J Mcmahon
Journal:  Children (Basel)       Date:  2022-06-30

Review 5.  There is urgent need to treat atherosclerotic cardiovascular disease risk earlier, more intensively, and with greater precision: A review of current practice and recommendations for improved effectiveness.

Authors:  Michael E Makover; Michael D Shapiro; Peter P Toth
Journal:  Am J Prev Cardiol       Date:  2022-08-06
  5 in total

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