Literature DB >> 23232215

Proximal junctional kyphosis results in inferior SRS pain subscores in adult deformity patients.

Han Jo Kim1, Keith H Bridwell, Lawrence G Lenke, Moon Soo Park, Azeem Ahmad, Kwang-Sup Song, Chaiwat Piyaskulkaew, Stuart Hershman, Jeremy Fogelson, Addisu Mesfin.   

Abstract

STUDY
DESIGN: Retrospective comparative study.
OBJECTIVE: We aimed to examine the difference in clinical outcomes in proximal junctional kyphosis (PJK). SUMMARY OF BACKGROUND DATA: To date, PJK has been primarily a radiographical finding. Inferior outcomes associated with PJK have not been reported. We performed an analysis of PJK in adult deformity patients to identify risk factors and to evaluate clinical outcomes.
METHODS: A total of 364 patients at a single institution from 2002 to 2007 with adult scoliosis, with an average 3.5 years' follow-up were analyzed. Inclusion criteria were age more than 18 years and fusion greater than 5 levels from any thoracic upper instrumented vertebrae to any lower instrumented vertebrae. Cobb measurements in the coronal and sagittal plane in addition to measurements of the PJK angle at postoperative time points were performed. Clinical assessment was performed using Scoliosis Research Society (SRS) scores and the Oswestry Disability Index.
RESULTS: The prevalence of PJK was 39.5% (144/364). The average age in the non-PJK group (n-PJK) was 48.9 versus 53.3 in the PJK group (PJK), and, specifically, age more than 60 years posed a higher prevalence. The prevalence of osteoporosis was 9.8% versus 20.4% in the n-PJK versus PJK groups, respectively. Sex, body mass index, revision surgery, and smoking status were not different between groups. Pain was prevalent in 0.9% versus 29.4% in n-PJK versus PJK, which resulted in lower composite SRS Pain scores (mean change +1.2 vs. +0.8), despite no differences seen in other SRS domains, total SRS score, or Oswestry Disability Index. On multivariate analysis, the presence of pain of the upper back was highly predictive of PJK (odds ratio, 12.5, 95% confidence interval, 2.5-63.2). Radiographically, no differences were seen between groups. However, increasing distance of the upper instrumented vertebrae to C7 plumb line had a higher prevalence of PJK. Instrumentation type, surgical approach, and crosslink use were not different between groups.
CONCLUSION: PJK results in worse clinical outcomes measured by the SRS Pain subscore. Our regression model suggests that pain in the upper back has a strong predictive value for PJK. LEVEL OF EVIDENCE: 3.

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Year:  2013        PMID: 23232215     DOI: 10.1097/BRS.0b013e3182815b42

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  36 in total

1.  Cervical sagittal deformity develops after PJK in adult thoracolumbar deformity correction: radiographic analysis utilizing a novel global sagittal angular parameter, the CTPA.

Authors:  Themistocles Protopsaltis; Nicolas Bronsard; Alex Soroceanu; Jensen K Henry; Renaud Lafage; Justin Smith; Eric Klineberg; Gregory Mundis; Han Jo Kim; Richard Hostin; Robert Hart; Christopher Shaffrey; Shay Bess; Christopher Ames
Journal:  Eur Spine J       Date:  2016-07-20       Impact factor: 3.134

Review 2.  Proximal junctional kyphosis and failure-diagnosis, prevention, and treatment.

Authors:  Ngoc-Lam M Nguyen; Christopher Y Kong; Robert A Hart
Journal:  Curr Rev Musculoskelet Med       Date:  2016-09

3.  Reply to letter to the editor: Combined anterior-posterior surgery is the most important risk factor for developing proximal junctional kyphosis in idiopathic scoliosis.

Authors:  Han Jo Kim
Journal:  Clin Orthop Relat Res       Date:  2013-03       Impact factor: 4.176

Review 4.  Proximal junctional kyphosis following adult spinal deformity surgery.

Authors:  Samuel K Cho; John I Shin; Yongjung J Kim
Journal:  Eur Spine J       Date:  2014-09-04       Impact factor: 3.134

Review 5.  Incidence and risk factors of proximal junctional kyphosis after internal fixation for adult spinal deformity: a systematic evaluation and meta-analysis.

Authors:  Jian Zhao; Kai Chen; Xiao Zhai; Kai Chen; Ming Li; Yanghu Lu
Journal:  Neurosurg Rev       Date:  2020-05-19       Impact factor: 3.042

6.  Proximal Junctional Kyphosis Prevention Strategies: A Video Technique Guide.

Authors:  Michael M Safaee; Joseph A Osorio; Kushagra Verma; Shay Bess; Christopher I Shaffrey; Justin S Smith; Robert Hart; Vedat Deviren; Christopher P Ames
Journal:  Oper Neurosurg (Hagerstown)       Date:  2017-10-01       Impact factor: 2.703

Review 7.  The importance of sagittal balance in adult scoliosis surgery.

Authors:  Jason Pui Yin Cheung
Journal:  Ann Transl Med       Date:  2020-01

8.  Proximal junctional kyphosis in adult spinal deformity with long spinal fusion from T9/T10 to the ilium.

Authors:  Tatsuya Yasuda; Tomohiko Hasegawa; Yu Yamato; Sho Kobayashi; Daisuke Togawa; Shin Oe; Yukihiro Matsuyama
Journal:  J Spine Surg       Date:  2017-06

9.  Degenerative lumbar scoliosis patients with proximal junctional kyphosis have lower muscularity, fatty degeneration at the lumbar area.

Authors:  Lei Yuan; Yan Zeng; Zhongqiang Chen; Weishi Li; Xinling Zhang; Shuo Mai
Journal:  Eur Spine J       Date:  2020-11-19       Impact factor: 3.134

10.  Incidence and risk factors for proximal junctional kyphosis: a meta-analysis.

Authors:  Feng-Yu Liu; Tao Wang; Si-Dong Yang; Hui Wang; Da-Long Yang; Wen-Yuan Ding
Journal:  Eur Spine J       Date:  2016-03-19       Impact factor: 3.134

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