Literature DB >> 2323221

Histological changes in the vas deferens of rats after injection of a new male antifertility agent "SMA" and its reversibility.

N Sethi1, R K Srivastava, R K Singh.   

Abstract

A new male antifertility agent, styrene maleic anhydride (SMA) dissolved in dimethyl sulphoxide (DMSO), was injected into the vas deferens of rats. The morphological changes detected were confined only to the mucosa. After four weeks, the vas deferens lumen was flushed with the solvent DMSO, and the mucosal structures returned to normal.

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Year:  1990        PMID： 2323221     DOI： 10.1016/0010-7824(90)90074-6

Source DB:  PubMed          Journal:  Contraception        ISSN： 0010-7824            Impact factor:   3.375


  3 in total

Review 1.  RISUG: an intravasal injectable male contraceptive.

Authors:  N K Lohiya; I Alam; M Hussain; S R Khan; A S Ansari
Journal:  Indian J Med Res       Date:  2014-11       Impact factor: 2.375

2.  Contraception with RISUG® and functional reversal through DMSO and NaHCO3 in male rabbits.

Authors:  Abdul S Ansari; Ayesha Badar; Krithika Balasubramanian; Nirmal K Lohiya
Journal:  Asian J Androl       Date:  2017 Jul-Aug       Impact factor: 3.285

3.  RISUG® as a male contraceptive: journey from bench to bedside.

Authors:  Barkha Khilwani; Ayesha Badar; Abdul S Ansari; Nirmal K Lohiya
Journal:  Basic Clin Androl       Date:  2020-02-13
  3 in total

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