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Literature DB >> 23229477

Plasmid content of a clinically relevant Klebsiella pneumoniae clone from the Czech Republic producing CTX-M-15 and QnrB1.

Monika Dolejska¹, Laura Villa, Hana Dobiasova, Daniela Fortini, Claudia Feudi, Alessandra Carattoli.

Abstract

The entire plasmid content of a multidrug-resistant, CTX-M-15-producing Klebsiella pneumoniae ST416 clone was investigated. Two FII(K) plasmids, pKDO1 (127 kb) and pKPN-CZ (207 kb), were identified and found to carry a formidable set of genes conferring resistance to toxic compounds, metals, and antimicrobial drugs and exhibiting novel features putatively associated with adaptation and fitness of the bacterium in the human host.

Entities: Gene Species

Mesh：

Substances：

Year: 2012 PMID： 23229477 PMCID： PMC3553734 DOI： 10.1128/AAC.01886-12

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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