Literature DB >> 2322931

Xanthine oxidase levels in human brain tumors.

E Kökoglu1, A Belce, E Ozyurt, Z Tepeler.   

Abstract

Xanthine oxidase is most recognized for its role as the rate-limiting enzyme in nucleic acid degradation through which all purines are channelled for terminal oxidation. The enzyme serves as a source of oxygen-derived free radicals which induce both cellular injury and edema as well as changes in vascular permeability. In the study we compared xanthine oxidase levels of human brain tumors with normal brain tissues. Statistical evaluation of our results shows significantly higher xanthine oxidase levels in tumoral brain tissues. However, xanthine oxidase has not any significance for the differentiation of tumor types among each others. The oncotypes studied were meningioma and astrocytoma.

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Year:  1990        PMID: 2322931     DOI: 10.1016/0304-3835(90)90262-v

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  12 in total

Review 1.  Wine as a biological fluid: history, production, and role in disease prevention.

Authors:  G J Soleas; E P Diamandis; D M Goldberg
Journal:  J Clin Lab Anal       Date:  1997       Impact factor: 2.352

2.  Lipid peroxidation and activity of some antioxidant enzymes in patients with glioblastoma and astrocytoma.

Authors:  Bartosz Woźniak; Alina Woźniak; Heliodor A Kasprzak; Gerard Drewa; Celestyna Mila-Kierzenkowska; Tomasz Drewa; Grzegorz Planutis
Journal:  J Neurooncol       Date:  2006-06-14       Impact factor: 4.130

Review 3.  The double faced role of xanthine oxidoreductase in cancer.

Authors:  Man-Man Chen; Ling-Hua Meng
Journal:  Acta Pharmacol Sin       Date:  2021-11-22       Impact factor: 7.169

4.  Levels of water-soluble antioxidants in astrocytoma and in adjacent tumor-free tissue.

Authors:  H Landolt; H Langemann; A Probst; O Gratzl
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

5.  Levels of certain tumor markers as differential factors between bilharzial and non-biharzial bladder cancer among Egyptian patients.

Authors:  Nadia S Metwally; Sanaa A Ali; Azza M Mohamed; Hussein M Khaled; Samia A Ahmed
Journal:  Cancer Cell Int       Date:  2011-04-07       Impact factor: 5.722

6.  1'-Acetoxychavicol acetate promotes caspase 3-activated glioblastoma cell death by overcoming enhanced cytokine expression.

Authors:  Musa Williams; Illya Tietzel; Quincy A Quick
Journal:  Oncol Lett       Date:  2013-04-05       Impact factor: 2.967

Review 7.  Xanthine oxidoreductase in cancer: more than a differentiation marker.

Authors:  Maria Giulia Battelli; Letizia Polito; Massimo Bortolotti; Andrea Bolognesi
Journal:  Cancer Med       Date:  2015-12-21       Impact factor: 4.452

8.  Metabolomic screening of pre-diagnostic serum samples identifies association between α- and γ-tocopherols and glioblastoma risk.

Authors:  Benny Björkblom; Carl Wibom; Pär Jonsson; Lina Mörén; Ulrika Andersson; Tom Børge Johannesen; Hilde Langseth; Henrik Antti; Beatrice Melin
Journal:  Oncotarget       Date:  2016-06-14

9.  Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.

Authors:  Sukirti Kalra; Gopabandhu Jena; Kulbhushan Tikoo; Anup Kumar Mukhopadhyay
Journal:  BMC Biochem       Date:  2007-05-18       Impact factor: 4.059

10.  Chemoprevention of azoxymethane-induced rat colon carcinogenesis by a xanthine oxidase inhibitor, 1'-acetoxychavicol acetate.

Authors:  T Tanaka; K Kawabata; M Kakumoto; H Makita; K Matsunaga; H Mori; K Satoh; A Hara; A Murakami; K Koshimizu; H Ohigashi
Journal:  Jpn J Cancer Res       Date:  1997-09
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