| Literature DB >> 2322931 |
E Kökoglu1, A Belce, E Ozyurt, Z Tepeler.
Abstract
Xanthine oxidase is most recognized for its role as the rate-limiting enzyme in nucleic acid degradation through which all purines are channelled for terminal oxidation. The enzyme serves as a source of oxygen-derived free radicals which induce both cellular injury and edema as well as changes in vascular permeability. In the study we compared xanthine oxidase levels of human brain tumors with normal brain tissues. Statistical evaluation of our results shows significantly higher xanthine oxidase levels in tumoral brain tissues. However, xanthine oxidase has not any significance for the differentiation of tumor types among each others. The oncotypes studied were meningioma and astrocytoma.Entities:
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Year: 1990 PMID: 2322931 DOI: 10.1016/0304-3835(90)90262-v
Source DB: PubMed Journal: Cancer Lett ISSN: 0304-3835 Impact factor: 8.679