Akihito Matsushita1, Minoru Tabata2, Toshihiro Fukui1, Yasunori Sato3, Shigefumi Matsuyama4, Tomoki Shimokawa4, Shuichiro Takanashi1. 1. Department of Cardiovascular Surgery, Sakakibara Heart institute, Tokyo, Japan. 2. Department of Cardiovascular Surgery, Sakakibara Heart institute, Tokyo, Japan. Electronic address: mtabata@post.harvard.edu. 3. Clinical Research Center, Graduate School of Medicine, Chiba University, Chiba, Japan. 4. Department of Cardiovascular Surgery, Teikyo University Hospital, Tokyo, Japan.
Abstract
OBJECTIVES: We sought to evaluate surgical outcomes of type A acute aortic dissection in elderly patients. METHODS: Between January 2004 and July 2011, 422 patients underwent emergency open surgery for type A acute aortic dissection at our institution. Of those, 124 patients who were ≥75 years (mean age, 78.6 ± 3.4 years) were reviewed. We also reviewed 26 patients (≥75 years old) who were diagnosed with acute aortic dissection at our institution during the same period but who did not undergo surgery. We analyzed early and late outcomes of surgical and nonsurgical patients. RESULTS: The operative mortality was 4.8% (6/124), and the incidences of stroke and prolonged hospital stay (>30 days) were 17.7% (22/124) and 20.1% (25/124), respectively. The actuarial survivals at 1, 3, and 5 years were 89.3%, 84.7%, and 79.1%, respectively. Predictors of stroke are preoperative cardiopulmonary resuscitation (odds ratio, 17.5; 95% confidence interval, 3.1-98.9; P = .001) and previous cardiac surgery (odds ratio, 14.0; 95% confidence interval, 1.2-164.7; P = .036). The 30-day or in-hospital mortality of patients who were indicated for surgery but refused surgery was 63.6% (7/11). CONCLUSIONS: Emergency open surgery for type A acute aortic dissection in elderly patients resulted in a low mortality but high incidences of stroke and prolonged hospital stay. Preoperative cardiopulmonary resuscitation and previous cardiac surgery were significant predictors of stroke. Emergency surgery is still the primary option for most elderly patients with acute aortic dissection.
OBJECTIVES: We sought to evaluate surgical outcomes of type A acute aortic dissection in elderly patients. METHODS: Between January 2004 and July 2011, 422 patients underwent emergency open surgery for type A acute aortic dissection at our institution. Of those, 124 patients who were ≥75 years (mean age, 78.6 ± 3.4 years) were reviewed. We also reviewed 26 patients (≥75 years old) who were diagnosed with acute aortic dissection at our institution during the same period but who did not undergo surgery. We analyzed early and late outcomes of surgical and nonsurgical patients. RESULTS: The operative mortality was 4.8% (6/124), and the incidences of stroke and prolonged hospital stay (>30 days) were 17.7% (22/124) and 20.1% (25/124), respectively. The actuarial survivals at 1, 3, and 5 years were 89.3%, 84.7%, and 79.1%, respectively. Predictors of stroke are preoperative cardiopulmonary resuscitation (odds ratio, 17.5; 95% confidence interval, 3.1-98.9; P = .001) and previous cardiac surgery (odds ratio, 14.0; 95% confidence interval, 1.2-164.7; P = .036). The 30-day or in-hospital mortality of patients who were indicated for surgery but refused surgery was 63.6% (7/11). CONCLUSIONS: Emergency open surgery for type A acute aortic dissection in elderly patients resulted in a low mortality but high incidences of stroke and prolonged hospital stay. Preoperative cardiopulmonary resuscitation and previous cardiac surgery were significant predictors of stroke. Emergency surgery is still the primary option for most elderly patients with acute aortic dissection.