Literature DB >> 23228390

Possible link of pioglitazone with bladder cancer in Japanese patients with type 2 diabetes.

Kanta Fujimoto1, Yoshiyuki Hamamoto, Sachiko Honjo, Yukiko Kawasaki, Kanako Mori, Hisato Tatsuoka, Atsuko Matsuoka, Yoshiharu Wada, Hiroki Ikeda, Jun Fujikawa, Hiroyuki Koshiyama.   

Abstract

We retrospectively examined the frequency of bladder cancer in Japanese patients with type 2 diabetes in relation to use of pioglitazone. Among a total of 663 patients identified to be taking pioglitazone, 9 had bladder cancer (1.36%). Overall the hazard ratio of 1.75 [95% CI: 0.89-3.45] for pioglitazone for bladder cancer was not significant. However the prevalence of bladder cancer was 2.10% in patients taking pioglitazone for less than 24 months which was significant increased (HR 2.73 [95% CI: 1.11-6.72]).
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 23228390     DOI: 10.1016/j.diabres.2012.11.013

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  14 in total

1.  Comparative safety of pioglitazone versus clinically meaningful treatment alternatives concerning the risk of bladder cancer in older US adults with type 2 diabetes.

Authors:  Elizabeth M Garry; John B Buse; Jennifer L Lund; Virginia Pate; Til Stürmer
Journal:  Diabetes Obes Metab       Date:  2017-08-08       Impact factor: 6.577

Review 2.  The future of thiazolidinedione therapy in the management of type 2 diabetes mellitus.

Authors:  Hanford Yau; Kathya Rivera; Romina Lomonaco; Kenneth Cusi
Journal:  Curr Diab Rep       Date:  2013-06       Impact factor: 4.810

3.  Study design choices for evaluating the comparative safety of diabetes medications: An evaluation of pioglitazone use and risk of bladder cancer in older US adults with type-2 diabetes.

Authors:  Elizabeth M Garry; John B Buse; Mugdha Gokhale; Jennifer L Lund; Matthew E Nielsen; Virginia Pate; Til Stürmer
Journal:  Diabetes Obes Metab       Date:  2019-06-17       Impact factor: 6.577

4.  Thiazolidinediones and associated risk of bladder cancer: a systematic review and meta-analysis.

Authors:  Richard M Turner; Chun S Kwok; Chen Chen-Turner; Chinedu A Maduakor; Sonal Singh; Yoon K Loke
Journal:  Br J Clin Pharmacol       Date:  2014-08       Impact factor: 4.335

5.  Pioglitazone use and risk of bladder cancer: a systematic literature review and meta-analysis of observational studies.

Authors:  Juha Mehtälä; Houssem Khanfir; Dimitri Bennett; Yizhou Ye; Pasi Korhonen; Fabian Hoti
Journal:  Diabetol Int       Date:  2018-06-14

6.  Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis.

Authors:  Daniel Levin; Samira Bell; Reijo Sund; Sirpa A Hartikainen; Jaakko Tuomilehto; Eero Pukkala; Ilmo Keskimäki; Ellena Badrick; Andrew G Renehan; Iain E Buchan; Samantha L Bowker; Jasjeet K Minhas-Sandhu; Zafar Zafari; Carlo Marra; Jeffrey A Johnson; Bruno H Stricker; Andrè G Uitterlinden; Albert Hofman; Rikje Ruiter; Catherine E de Keyser; Thomas M MacDonald; Sarah H Wild; Paul M McKeigue; Helen M Colhoun
Journal:  Diabetologia       Date:  2014-12-07       Impact factor: 10.122

7.  Pioglitazone: A prudent prescription.

Authors:  Sanjay Kalra; Puneet Dhamija; Rakesh Sahay
Journal:  Indian J Endocrinol Metab       Date:  2013-05

8.  Risk of bladder cancer among patients with diabetes treated with a 15 mg pioglitazone dose in Korea: a multi-center retrospective cohort study.

Authors:  Sang-Man Jin; Sun Ok Song; Chang Hee Jung; Jin-Sun Chang; Sunghwan Suh; Seung Min Kang; Inkyung Jung; Cheol-Young Park; Jae Hyeon Kim; Jae Hyoung Cho; Byung-Wan Lee
Journal:  J Korean Med Sci       Date:  2014-01-28       Impact factor: 2.153

9.  Pioglitazone use and risk of bladder cancer: population based cohort study.

Authors:  Marco Tuccori; Kristian B Filion; Hui Yin; Oriana H Yu; Robert W Platt; Laurent Azoulay
Journal:  BMJ       Date:  2016-03-30

10.  Generalized enrichment analysis improves the detection of adverse drug events from the biomedical literature.

Authors:  Rainer Winnenburg; Nigam H Shah
Journal:  BMC Bioinformatics       Date:  2016-06-23       Impact factor: 3.169

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