Literature DB >> 23225069

Assessing the effects of drug misuse on HIV/AIDS prevalence.

C P Bhunu1, S Mushayabasa.   

Abstract

Drug misuse (injecting drug users-IDU) has been recognized to have a significant effect on the spread of HIV/AIDS epidemic. A deterministic model to assess the contribution of drug misuse and sex in the spread of HIV/AIDS is investigated. The threshold parameters of the model are determined and stabilities are analysed. Analysis of the reproduction number has shown that increase in drug misuse results in an increase in HIV infections. Furthermore, numerical simulations of the model show that drug misuse enhances HIV transmission and progression to AIDS. Thus, in a population with intravenous drug users, advocating for safe sex alone will not be enough to control the HIV/AIDS epidemic.

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Year:  2012        PMID： 23225069     DOI： 10.1007/s12064-012-0171-2

Source DB:  PubMed          Journal:  Theory Biosci        ISSN： 1431-7613            Impact factor:   1.919


  18 in total

1.  The differential infectivity and staged progression models for the transmission of HIV.

Authors:  J M Hyman; J Li; E A Stanley
Journal:  Math Biosci       Date:  1999-02       Impact factor: 2.144

2.  Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission.

Authors:  P van den Driessche; James Watmough
Journal:  Math Biosci       Date:  2002 Nov-Dec       Impact factor: 2.144

3.  AIDS epidemic update: December 1999.

Authors: 
Journal:  AIDS Anal Afr       Date:  2000 Feb-Mar

4.  A theoretical assessment of the effects of smoking on the transmission dynamics of tuberculosis.

Authors:  C P Bhunu; S Mushayabasa; J M Tchuenche
Journal:  Bull Math Biol       Date:  2010-08-20       Impact factor: 1.758

5.  Drugs, sex and HIV: a mathematical model for New York City.

Authors:  S M Blower; D Hartel; H Dowlatabadi; R M Anderson; R M May
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1991-02-28       Impact factor: 6.237

6.  Mathematical analysis of a two strain HIV/AIDS model with antiretroviral treatment.

Authors:  C P Bhunu; W Garira; G Magombedze
Journal:  Acta Biotheor       Date:  2009-04-09       Impact factor: 1.774

7.  Gender differences in injection risk behaviors at the first injection episode.

Authors:  Vera Frajzyngier; Alan Neaigus; V Anna Gyarmathy; Maureen Miller; Samuel R Friedman
Journal:  Drug Alcohol Depend       Date:  2007-02-05       Impact factor: 4.492

8.  Effect of hard-drug use on CD4 cell percentage, HIV RNA level, and progression to AIDS-defining class C events among HIV-infected women.

Authors:  Lorna E Thorpe; Margaret Frederick; Jane Pitt; Irene Cheng; D Heather Watts; Shelley Buschur; Karen Green; Carmen Zorrilla; Sheldon H Landesman; Ronald C Hershow
Journal:  J Acquir Immune Defic Syndr       Date:  2004-11-01       Impact factor: 3.731

Review 9.  The association between HIV infection and alcohol use: a systematic review and meta-analysis of African studies.

Authors:  Joseph C Fisher; Heejung Bang; Saidi H Kapiga
Journal:  Sex Transm Dis       Date:  2007-11       Impact factor: 2.830

10.  Injection drug use and HIV/AIDS in China: review of current situation, prevention and policy implications.

Authors:  Han-Zhu Qian; Joseph E Schumacher; Huey T Chen; Yu-Hua Ruan
Journal:  Harm Reduct J       Date:  2006-02-01
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  1 in total

1.  On the global stability of an epidemic model of computer viruses.

Authors:  Mohammad Reza Parsaei; Reza Javidan; Narges Shayegh Kargar; Hassan Saberi Nik
Journal:  Theory Biosci       Date:  2017-08-03       Impact factor: 1.919
  1 in total

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