Literature DB >> 23224865

Livin' with NCX and lovin' it: a 45 year romance.

Mordecai P Blaustein1.   

Abstract

This conference commemorates, almost to the day, the 45th anniversary of the discovery of the Na(+)/Ca(2+) exchanger (NCX). The discovery was serendipitous, as is so often the case with scientific breakthroughs. Indeed, that is what is so fascinating and romantic about scientific research. I will describe the discovery of NCX, but will begin by explaining how I got there, and will then discuss how the discovery influenced my career path.

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Year:  2013        PMID: 23224865      PMCID: PMC3884827          DOI: 10.1007/978-1-4614-4756-6_1

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  73 in total

1.  Different relationship of N- and P/Q-type Ca2+ channels to channel-interacting slots in controlling neurotransmission at cultured hippocampal synapses.

Authors:  Yu-Qing Cao; Richard W Tsien
Journal:  J Neurosci       Date:  2010-03-31       Impact factor: 6.167

2.  Identification and characterization of a ouabain-like compound from human plasma.

Authors:  J M Hamlyn; M P Blaustein; S Bova; D W DuCharme; D W Harris; F Mandel; W R Mathews; J H Ludens
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

3.  Synaptic vesicle recycling in synaptosomes in vitro.

Authors:  R C Fried; M P Blaustein
Journal:  Nature       Date:  1976-05-20       Impact factor: 49.962

Review 4.  The interrelationship between sodium and calcium fluxes across cell membranes.

Authors:  M P Blaustein
Journal:  Rev Physiol Biochem Pharmacol       Date:  1974       Impact factor: 5.545

5.  ATP-dependent calcium storage in presynaptic nerve terminals.

Authors:  N C Kendrick; M P Blaustein; R C Fried; R W Ratzlaff
Journal:  Nature       Date:  1977-01-20       Impact factor: 49.962

Review 6.  Signal transduction and regulation in smooth muscle.

Authors:  A P Somlyo; A V Somlyo
Journal:  Nature       Date:  1994-11-17       Impact factor: 49.962

7.  Ouabain augments Ca(2+) transients in arterial smooth muscle without raising cytosolic Na(+).

Authors:  A Arnon; J M Hamlyn; M P Blaustein
Journal:  Am J Physiol Heart Circ Physiol       Date:  2000-08       Impact factor: 4.733

8.  Descending vasa recta pericytes express voltage operated Na+ conductance in the rat.

Authors:  Zhong Zhang; Chunhua Cao; Whaseon Lee-Kwon; Thomas L Pallone
Journal:  J Physiol       Date:  2005-06-23       Impact factor: 5.182

9.  Enhancement of receptor-operated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats.

Authors:  Young Min Bae; Aeran Kim; Young Joo Lee; Wonchung Lim; Yun-Hee Noh; Eun-Ju Kim; Junghwan Kim; Tae-Kyung Kim; Sang Woong Park; Bokyung Kim; Sung Il Cho; Duk-Kyung Kim; Won-Kyung Ho
Journal:  J Hypertens       Date:  2007-04       Impact factor: 4.844

10.  Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension.

Authors:  Ying Yu; Ivana Fantozzi; Carmelle V Remillard; Judd W Landsberg; Naomi Kunichika; Oleksandr Platoshyn; Donna D Tigno; Patricia A Thistlethwaite; Lewis J Rubin; Jason X-J Yuan
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-09       Impact factor: 11.205

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  3 in total

Review 1.  The pump, the exchanger, and the holy spirit: origins and 40-year evolution of ideas about the ouabain-Na+ pump endocrine system.

Authors:  Mordecai P Blaustein
Journal:  Am J Physiol Cell Physiol       Date:  2017-11-07       Impact factor: 4.249

2.  Senescence Is Associated With Elevated Intracellular Resting [Ca2 +] in Mice Skeletal Muscle Fibers. An in vivo Study.

Authors:  Alfredo Mijares; Paul D Allen; Jose R Lopez
Journal:  Front Physiol       Date:  2021-01-12       Impact factor: 4.566

Review 3.  Specialized Functional Diversity and Interactions of the Na,K-ATPase.

Authors:  Vladimir V Matchkov; Igor I Krivoi
Journal:  Front Physiol       Date:  2016-05-25       Impact factor: 4.566

  3 in total

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