Literature DB >> 23224515

Viewing social scenes: a visual scan-path study comparing fragile X syndrome and Williams syndrome.

Tracey A Williams1, Melanie A Porter, Robyn Langdon.   

Abstract

Fragile X syndrome (FXS) and Williams syndrome (WS) are both genetic disorders which present with similar cognitive-behavioral problems, but distinct social phenotypes. Despite these social differences both syndromes display poor social relations which may result from abnormal social processing. This study aimed to manipulate the location of socially salient information within scenes to investigate the visual attentional mechanisms of: capture, disengagement, and/or general engagement. Findings revealed that individuals with FXS avoid social information presented centrally, at least initially. The WS findings, on the other hand, provided some evidence that difficulties with attentional disengagement, rather than attentional capture, may play a role in the WS social phenotype. These findings are discussed in relation to the distinct social phenotypes of these two disorders.

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Mesh:

Year:  2013        PMID: 23224515     DOI: 10.1007/s10803-012-1737-z

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  59 in total

1.  Neural correlates of genetically abnormal social cognition in Williams syndrome.

Authors:  Andreas Meyer-Lindenberg; Ahmad R Hariri; Karen E Munoz; Carolyn B Mervis; Venkata S Mattay; Colleen A Morris; Karen Faith Berman
Journal:  Nat Neurosci       Date:  2005-07-10       Impact factor: 24.884

2.  ADHD symptoms in children with FXS.

Authors:  Kelly Sullivan; Deborah Hatton; Julie Hammer; John Sideris; Stephen Hooper; Peter Ornstein; Donald Bailey
Journal:  Am J Med Genet A       Date:  2006-11-01       Impact factor: 2.802

3.  Cognitive profiles associated with the fra(X) syndrome in males and females.

Authors:  L S Freund; A L Reiss
Journal:  Am J Med Genet       Date:  1991-03-15

4.  Differential impact of the FMR-1 full mutation on memory and attention functioning : a neuropsychological perspective.

Authors:  K M Cornish; F Munir; G Cross
Journal:  J Cogn Neurosci       Date:  2001-01-01       Impact factor: 3.225

5.  Spatial representation and attention in toddlers with Williams syndrome and Down syndrome.

Authors:  Janice H Brown; Mark H Johnson; Sarah J Paterson; Rick Gilmore; Elena Longhi; Annette Karmiloff-Smith
Journal:  Neuropsychologia       Date:  2003       Impact factor: 3.139

6.  Further delineation of the executive deficit in males with fragile-X syndrome.

Authors:  John Wilding; Kim Cornish; Fehmidah Munir
Journal:  Neuropsychologia       Date:  2002       Impact factor: 3.139

7.  Autism spectrum disorder in fragile X syndrome: communication, social interaction, and specific behaviors.

Authors:  Walter E Kaufmann; Ranon Cortell; Alice S M Kau; Irena Bukelis; Elaine Tierney; Robert M Gray; Christiane Cox; George T Capone; Pia Stanard
Journal:  Am J Med Genet A       Date:  2004-09-01       Impact factor: 2.802

8.  Behavioral and emotional disturbance in individuals with Williams syndrome.

Authors:  S L Einfeld; B J Tonge; T Florio
Journal:  Am J Ment Retard       Date:  1997-07

9.  Brain function and gaze fixation during facial-emotion processing in fragile X and autism.

Authors:  Kim M Dalton; Laura Holsen; Leonard Abbeduto; Richard J Davidson
Journal:  Autism Res       Date:  2008-08       Impact factor: 5.216

10.  Reliability of eye tracking and pupillometry measures in individuals with fragile X syndrome.

Authors:  Faraz Farzin; Felicia Scaggs; Crystal Hervey; Elizabeth Berry-Kravis; David Hessl
Journal:  J Autism Dev Disord       Date:  2011-11
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  6 in total

1.  Effects of labeling and pointing on object gaze in boys with fragile X syndrome: an eye-tracking study.

Authors:  David P Benjamin; Ann M Mastergeorge; Andrea S McDuffie; Sara T Kover; Randi J Hagerman; Leonard Abbeduto
Journal:  Res Dev Disabil       Date:  2014-07-23

2.  Quantifying naturalistic social gaze in fragile X syndrome using a novel eye tracking paradigm.

Authors:  Scott S Hall; Michael C Frank; Guido T Pusiol; Faraz Farzin; Amy A Lightbody; Allan L Reiss
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2015-06-16       Impact factor: 3.568

3.  Early social communication in infants with fragile X syndrome and infant siblings of children with autism spectrum disorder.

Authors:  Laura J Hahn; Nancy C Brady; Lindsay McCary; Lisa Rague; Jane E Roberts
Journal:  Res Dev Disabil       Date:  2017-10-15

Review 4.  Williams syndrome and its cognitive profile: the importance of eye movements.

Authors:  Jo Van Herwegen
Journal:  Psychol Res Behav Manag       Date:  2015-06-03

5.  Visual preference for social stimuli in individuals with autism or neurodevelopmental disorders: an eye-tracking study.

Authors:  Hayley Crawford; Joanna Moss; Chris Oliver; Natasha Elliott; Giles M Anderson; Joseph P McCleery
Journal:  Mol Autism       Date:  2016-04-05       Impact factor: 7.509

Review 6.  Overview of Social Cognitive Dysfunctions in Rare Developmental Syndromes With Psychiatric Phenotype.

Authors:  Aurore Morel; Elodie Peyroux; Arnaud Leleu; Emilie Favre; Nicolas Franck; Caroline Demily
Journal:  Front Pediatr       Date:  2018-05-03       Impact factor: 3.418

  6 in total

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