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Literature DB >> 23223894

PTEN at a glance.

Yuji Shi¹, Benjamin E Paluch, Xinjiang Wang, Xuejun Jiang.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2012 PMID： 23223894 PMCID： PMC3517091 DOI： 10.1242/jcs.093765

Source DB: PubMed Journal: J Cell Sci ISSN： 0021-9533 Impact factor: 5.285

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69 in total

1. Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells.

Authors: Lizhi He; Alistair Ingram; Adrian P Rybak; Damu Tang
Journal: J Clin Invest Date: 2010-05-10 Impact factor: 14.808

2. NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.

Authors: Xinjiang Wang; Lloyd C Trotman; Theresa Koppie; Andrea Alimonti; Zhenbang Chen; Zhonghua Gao; Junru Wang; Hediye Erdjument-Bromage; Paul Tempst; Carlos Cordon-Cardo; Pier Paolo Pandolfi; Xuejun Jiang
Journal: Cell Date: 2007-01-12 Impact factor: 41.582

3. Increased protein expression of the PTEN tumor suppressor in the presence of constitutively active Notch-1.

Authors: William H Chappell; Thomas D Green; Justin D Spengeman; James A McCubrey; Shaw M Akula; Fred E Bertrand
Journal: Cell Cycle Date: 2005-10-13 Impact factor: 4.534

4. Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner.

Authors: Min Sup Song; Arkaitz Carracedo; Leonardo Salmena; Su Jung Song; Ainara Egia; Marcos Malumbres; Pier Paolo Pandolfi
Journal: Cell Date: 2011-01-21 Impact factor: 41.582

5. E3 ligase Nedd4 promotes axon branching by downregulating PTEN.

Authors: Jovana Drinjakovic; Hosung Jung; Douglas S Campbell; Laure Strochlic; Asha Dwivedy; Christine E Holt
Journal: Neuron Date: 2010-02-11 Impact factor: 17.173

6. NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration.

Authors: Young-Don Kwak; Tao Ma; Shiyong Diao; Xue Zhang; Yaomin Chen; Janet Hsu; Stuart A Lipton; Eliezer Masliah; Huaxi Xu; Francesca-Fang Liao
Journal: Mol Neurodegener Date: 2010-11-10 Impact factor: 14.195

Review 7. PTEN and the PI3-kinase pathway in cancer.

Authors: Nader Chalhoub; Suzanne J Baker
Journal: Annu Rev Pathol Date: 2009 Impact factor: 23.472

8. Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain.

Authors: Leticia Odriozola; Gobind Singh; Thuong Hoang; Andrew M Chan
Journal: J Biol Chem Date: 2007-06-12 Impact factor: 5.157

9. Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

Authors: Eun-Kyoung Yim; Guang Peng; Hui Dai; Ruozhen Hu; Kaiyi Li; Yiling Lu; Gordon B Mills; Funda Meric-Bernstam; Bryan T Hennessy; Rolf J Craven; Shiaw-Yih Lin
Journal: Cancer Cell Date: 2009-04-07 Impact factor: 31.743

10. The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

Authors: Min Sup Song; Leonardo Salmena; Arkaitz Carracedo; Ainara Egia; Francesco Lo-Coco; Julie Teruya-Feldstein; Pier Paolo Pandolfi
Journal: Nature Date: 2008-08-20 Impact factor: 49.962

44 in total

1. PTEN gene is infrequently hypermethylated in human esophageal squamous cell carcinoma.

Authors: Zhenguo Sun; Na Ji; Mingming Bi; Shuai Wang; Xiangyan Liu; Zhou Wang
Journal: Tumour Biol Date: 2015-02-28

Review 2. Turning off AKT: PHLPP as a drug target.

Authors: Alexandra C Newton; Lloyd C Trotman
Journal: Annu Rev Pharmacol Toxicol Date: 2014 Impact factor: 13.820

3. Mutations in PIK3R1 cause SHORT syndrome.

Authors: David A Dyment; Amanda C Smith; Diana Alcantara; Jeremy A Schwartzentruber; Lina Basel-Vanagaite; Cynthia J Curry; I Karen Temple; William Reardon; Sahar Mansour; Mushfequr R Haq; Rodney Gilbert; Ordan J Lehmann; Megan R Vanstone; Chandree L Beaulieu; Jacek Majewski; Dennis E Bulman; Mark O'Driscoll; Kym M Boycott; A Micheil Innes
Journal: Am J Hum Genet Date: 2013-06-27 Impact factor: 11.025

PTEN at a glance.

1. Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells.

2. NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.

3. Increased protein expression of the PTEN tumor suppressor in the presence of constitutively active Notch-1.

4. Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner.

5. E3 ligase Nedd4 promotes axon branching by downregulating PTEN.

6. NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration.

Review 7. PTEN and the PI3-kinase pathway in cancer.

8. Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain.

9. Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

10. The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

1. PTEN gene is infrequently hypermethylated in human esophageal squamous cell carcinoma.

Review 2. Turning off AKT: PHLPP as a drug target.

3. Mutations in PIK3R1 cause SHORT syndrome.

4. Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses.

5. miR-205 regulates A549 cells proliferation by targeting PTEN.

6. Cutting Edge: Differential Regulation of PTEN by TCR, Akt, and FoxO1 Controls CD4+ T Cell Fate Decisions.

Review 7. The Role of PTEN in Neurodevelopment.

8. Good news for the ageing beta cell.

9. Long-term consequences of conditional genetic deletion of PTEN in the sensorimotor cortex of neonatal mice.

10. Regulatory Effects and Mechanism of Adenovirus-Mediated PTEN Gene on Hepatic Stellate Cells.