Literature DB >> 23223564

Consent of the recently bereaved to post-mortem targeted angiography research: 207 adult cases.

Sarah L Saunders1, Jasmin Amoroso, Bruno Morgan, Guy Rutty.   

Abstract

AIMS: To present our experience of prospective telephone consenting for post-mortem CT angiography (PMCT-A) research using HM coroners' cases.
METHODS: Local ethics committee, research and development office, and local HM coroners gave their permission for the families of the deceased, in cases where a 'routine' coroner's autopsy had been authorised, to be approached for their consent to PMCT-A research before the autopsy examination. A forensic pathologist or trial consenter telephoned the next of kin, discussed the nature of the study and obtained verbal informed consent for post-mortem imaging, angiography, case-dependent histological and toxicology sampling and for the use of the images for teaching and training. Thematic analyses of the reasons for giving or refusing consent are provided.
RESULTS: Of the 207 cases approached, seven relatives refused to enter their next of kin into the study (96.6% consent rate).
CONCLUSIONS: This study shows that prospective consenting for HM coroners' cases to be used for autopsy research is feasible in adults, and can be done ethically, and in the limited time available, by obtaining the consent of the next of kin by telephone before autopsy.

Entities:  

Mesh:

Year:  2012        PMID: 23223564     DOI: 10.1136/jclinpath-2012-201250

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  7 in total

1.  Post-mortem computed tomography ventilation; simulating breath holding.

Authors:  C Robinson; M J Biggs; J Amoroso; M Pakkal; B Morgan; G N Rutty
Journal:  Int J Legal Med       Date:  2013-11-26       Impact factor: 2.686

2.  Ventilated post-mortem computed tomography through the use of a definitive airway.

Authors:  Guy N Rutty; Mike J P Biggs; Alison Brough; Claire Robinson; Reena Mistry; Jasmin Amoroso; Aparna Deshpande; Bruno Morgan
Journal:  Int J Legal Med       Date:  2014-12-19       Impact factor: 2.686

3.  Coronary optical coherence tomography: minimally invasive virtual histology as part of targeted post-mortem computed tomography angiography.

Authors:  David Adlam; Shiju Joseph; Claire Robinson; Clement Rousseau; Jade Barber; Mike Biggs; Bruno Morgan; Guy Rutty
Journal:  Int J Legal Med       Date:  2013-02-28       Impact factor: 2.686

4.  The effect on cadaver blood DNA identification by the use of targeted and whole body post-mortem computed tomography angiography.

Authors:  Guy N Rutty; Jade Barber; Jasmin Amoroso; Bruno Morgan; Eleanor A M Graham
Journal:  Forensic Sci Med Pathol       Date:  2013-07-06       Impact factor: 2.007

5.  Autopsy of Adult Patients Deceased in an Academic Hospital: Considerations of Doctors and Next-of-Kin in the Consent Process.

Authors:  Britt M Blokker; Annick C Weustink; M G Myriam Hunink; J Wolter Oosterhuis
Journal:  PLoS One       Date:  2016-10-13       Impact factor: 3.240

6.  Post-mortem computed tomography coaxial cutting needle biopsy to facilitate the detection of bacterioplankton using PCR probes as a diagnostic indicator for drowning.

Authors:  Guy N Rutty; Christopher Johnson; Jasmin Amoroso; Claire Robinson; Carina J Bradley; Bruno Morgan
Journal:  Int J Legal Med       Date:  2016-11-05       Impact factor: 2.686

7.  Diagnostic accuracy of post-mortem CT with targeted coronary angiography versus autopsy for coroner-requested post-mortem investigations: a prospective, masked, comparison study.

Authors:  Guy N Rutty; Bruno Morgan; Claire Robinson; Vimal Raj; Mini Pakkal; Jasmin Amoroso; Theresa Visser; Sarah Saunders; Mike Biggs; Frances Hollingbury; Angus McGregor; Kevin West; Cathy Richards; Laurence Brown; Rebecca Harrison; Roger Hew
Journal:  Lancet       Date:  2017-05-24       Impact factor: 79.321

  7 in total

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