Literature DB >> 2322262

Parathyroid hormone related peptide can function as an autocrine growth factor in human renal cell carcinoma.

P B Burton1, C Moniz, D E Knight.   

Abstract

Parathyroid hormone related peptide (PTHrP) has been implicated in the cause of the hypercalcemia associated with a number of malignant tumours. The data presented here suggests that PTHrP (in addition to its known role of mediating hypercalcemia) may be involved in the autocrine regulation of growth of some tumours. Polyclonal PTHrP antiserum almost totally inhibited the growth of a human renal cell carcinoma cell line, known to secrete PTHrP, in vitro and growth was significantly inhibited by the competitive PTH antagonist PTH (3-34)NH2.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2322262     DOI： 10.1016/0006-291x(90)90641-y

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  21 in total

Review 1.  Parathyroid-hormone-related peptides. A new class of multifunctional proteins.

Authors:  T Roskams; V Desmet
Journal:  Am J Pathol       Date:  1997-03       Impact factor: 4.307

2.  Combined hepatocellular-cholangiocarcinoma producing parathyroid hormone-related protein: report of a case.

Authors:  Michinori Matsumoto; Shigeki Wakiyama; Hiroaki Shiba; Takeshi Gocho; Takeyuki Misawa; Yuichi Ishida; Mariko Itsubo; Masafumi Suzuki; Katsuhiko Yanaga
Journal:  Surg Today       Date:  2013-09-08       Impact factor: 2.549

3.  Gastric cancer associated with overexpression of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor in relation to tumor progression.

Authors:  M Ito; M Nakashima; G K Alipov; S Matsuzaki; A Ohtsuru; H Yano; S Yamashita; I Sekine
Journal:  J Gastroenterol       Date:  1997-06       Impact factor: 7.527

4.  Transcriptional regulation of parathyroid hormone-related protein promoter P3 by ETS-1 in adult T-cell leukemia/lymphoma.

Authors:  V Richard; M V P Nadella; P L Green; M D Lairmore; G Feuer; J G Foley; T J Rosol
Journal:  Leukemia       Date:  2005-07       Impact factor: 11.528

5.  Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo.

Authors:  Wolfgang E Gallwitz; Theresa A Guise; Gregory R Mundy
Journal:  J Clin Invest       Date:  2002-11       Impact factor: 14.808

6.  Effect of parathyroid hormone related protein, and dihydrotestosterone on proliferation and ornithine decarboxylase mRNA in human prostate cancer cell lines.

Authors:  F Asadi; M Faraj; S Malakouti; S C Kukreja
Journal:  Int Urol Nephrol       Date:  2001       Impact factor: 2.370

Review 7.  Neuroendocrine peptides in the prostate.

Authors:  P J Gkonos; A Krongrad; B A Roos
Journal:  Urol Res       Date:  1995

8.  A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice.

Authors:  M F Holick; S Ray; T C Chen; X Tian; K S Persons
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-16       Impact factor: 11.205

9.  Prohormone convertase furin has a role in gastric cancer cell proliferation with parathyroid hormone-related peptide in a reciprocal manner.

Authors:  Toshio Nakajima; Yoshitaka Konda; Masashi Kanai; Yoshio Izumi; Naoki Kanda; Apichart Nanakin; Sohei Kitazawa; Tsutomu Chiba
Journal:  Dig Dis Sci       Date:  2002-12       Impact factor: 3.199

10.  Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.

Authors:  Astrid Rohrbeck; Jürgen Borlak
Journal:  PLoS One       Date:  2009-10-08       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.