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Literature DB >> 23220967

Lucilia sericata chymotrypsin disrupts protein adhesin-mediated staphylococcal biofilm formation.

Llinos G Harris¹, Yamni Nigam, James Sawyer, Dietrich Mack, David I Pritchard.

Abstract

Staphylococcus aureus and Staphylococcus epidermidis biofilms cause chronic infections due to their ability to form biofilms. The excretions/secretions of Lucilia sericata larvae (maggots) have effective activity for debridement and disruption of bacterial biofilms. In this paper, we demonstrate how chymotrypsin derived from maggot excretions/secretions disrupts protein-dependent bacterial biofilm formation mechanisms.

Entities: Disease Species

Mesh：

Substances：

Year: 2012 PMID： 23220967 PMCID： PMC3568615 DOI： 10.1128/AEM.03689-12

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

24 in total

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8. The antibacterial activity against MRSA strains and other bacteria of a <500Da fraction from maggot excretions/secretions of Lucilia sericata (Diptera: Calliphoridae).

Authors: Alyson Bexfield; A Elizabeth Bond; Emily C Roberts; Edward Dudley; Yamni Nigam; Stephen Thomas; Russell P Newton; Norman A Ratcliffe
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10. Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions.

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