| Literature DB >> 23219438 |
Volker Gerdts1, George Mutwiri, James Richards, Sylvia van Drunen Littel-van den Hurk, Andrew A Potter.
Abstract
The practice of immunization of animals and humans has been carried out for centuries and is generally accepted as the most cost effective and sustainable method of infectious disease control. Over the past 20 years there have been significant changes in our ability to produce antigens by conventional extraction and purification, recombinant DNA and synthesis. However, many of these products need to be combined with carrier molecules to generate optimal immune responses. This review covers selected topics in the development of carrier technologies for use in the veterinary vaccine field, including glycoconjugate and peptide vaccines, microparticle and nanoparticle formulations, and finally virus-like particles. CrownEntities:
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Year: 2012 PMID: 23219438 DOI: 10.1016/j.vaccine.2012.11.067
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641