OBJECTIVE: Arthritis is associated with cardiovascular diseases (CVDs). However, there are limited epidemiologic studies on arthritis in a national survey study. We therefore investigated the prevalence of self-reported arthritis and its association with CVDs. METHODS: Data from 15,888 subjects aged 40 years or older in the United States National Health and Nutrition Examination Survey 1999 through 2008 were analyzed. CVD was defined as a self-reported history of heart attack, congestive heart failure, coronary heart disease, angina, or stroke. RESULTS: The overall prevalence of self-reported arthritis in subjects aged 40 years or older increased from 33.5% in 1999 through 2000 to 37.0% in 2007 through 2008 (P for trend = 0.017). Among subjects with arthritis in 1999 through 2008, 35.3% had osteoarthritis (OA), 17.9% had rheumatoid arthritis (RA), and 10.2% had other types of arthritis, but 36.6% were unaware of their type of arthritis. Compared with subjects without OA, subjects with OA had higher odds for CVDs (odds ratio [OR], 1.53; P < .001), especially angina (OR, 2.18: P < .001). Compared with subjects without RA, subjects with RA had higher odds for CVDs (adjusted OR, 2.39; P < .001), especially congestive heart failure (OR, 3.59; P < .001). CONCLUSIONS: Both RA and OA are strongly associated with CVDs in the general population. Further studies are needed to investigate their causal relationship.
OBJECTIVE:Arthritis is associated with cardiovascular diseases (CVDs). However, there are limited epidemiologic studies on arthritis in a national survey study. We therefore investigated the prevalence of self-reported arthritis and its association with CVDs. METHODS: Data from 15,888 subjects aged 40 years or older in the United States National Health and Nutrition Examination Survey 1999 through 2008 were analyzed. CVD was defined as a self-reported history of heart attack, congestive heart failure, coronary heart disease, angina, or stroke. RESULTS: The overall prevalence of self-reported arthritis in subjects aged 40 years or older increased from 33.5% in 1999 through 2000 to 37.0% in 2007 through 2008 (P for trend = 0.017). Among subjects with arthritis in 1999 through 2008, 35.3% had osteoarthritis (OA), 17.9% had rheumatoid arthritis (RA), and 10.2% had other types of arthritis, but 36.6% were unaware of their type of arthritis. Compared with subjects without OA, subjects with OA had higher odds for CVDs (odds ratio [OR], 1.53; P < .001), especially angina (OR, 2.18: P < .001). Compared with subjects without RA, subjects with RA had higher odds for CVDs (adjusted OR, 2.39; P < .001), especially congestive heart failure (OR, 3.59; P < .001). CONCLUSIONS: Both RA and OA are strongly associated with CVDs in the general population. Further studies are needed to investigate their causal relationship.
Authors: Asheesh Bedi; Evan B Lynch; Elizabeth R Sibilsky Enselman; Max E Davis; Paul D Dewolf; Tarek A Makki; Bryan T Kelly; Christopher M Larson; Phillip T Henning; Christopher L Mendias Journal: Am J Sports Med Date: 2013-08-19 Impact factor: 6.202
Authors: L Kuusalo; D T Felson; N Wang; C E Lewis; J Torner; M C Nevitt; T Neogi Journal: Osteoarthritis Cartilage Date: 2020-11-27 Impact factor: 6.576
Authors: Bahram Mohajer; Ali Guermazi; Philip G Conaghan; Francis Berenbaum; Frank W Roemer; Arya Haj-Mirzaian; Clifton O Bingham; Kamyar Moradi; Xu Cao; Mei Wan; Shadpour Demehri Journal: Eur Radiol Date: 2022-01-19 Impact factor: 7.034