Literature DB >> 23217703

Cleaning up: ER-associated degradation to the rescue.

Jeffrey L Brodsky1.   

Abstract

All cellular proteins are subject to quality control "decisions," which help to prevent or delay a myriad of diseases. Quality control within the secretory pathway creates a special challenge, as aberrant polypeptides are recognized and returned to the cytoplasm for proteasomal degradation. This process is termed endoplasmic-reticulum (ER)-associated degradation (ERAD).
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23217703      PMCID: PMC3521611          DOI: 10.1016/j.cell.2012.11.012

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  30 in total

1.  A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation.

Authors:  Qiuyan Wang; Yanfen Liu; Nia Soetandyo; Kheewoong Baek; Ramanujan Hegde; Yihong Ye
Journal:  Mol Cell       Date:  2011-06-24       Impact factor: 17.970

Review 2.  Protein folding and modification in the mammalian endoplasmic reticulum.

Authors:  Ineke Braakman; Neil J Bulleid
Journal:  Annu Rev Biochem       Date:  2011       Impact factor: 23.643

3.  Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.

Authors:  Masatoshi Hagiwara; Ken-Ichi Maegawa; Mamoru Suzuki; Ryo Ushioda; Kazutaka Araki; Yushi Matsumoto; Jun Hoseki; Kazuhiro Nagata; Kenji Inaba
Journal:  Mol Cell       Date:  2011-02-18       Impact factor: 17.970

Review 4.  Cdc48: a power machine in protein degradation.

Authors:  Alexandra Stolz; Wolfgang Hilt; Alexander Buchberger; Dieter H Wolf
Journal:  Trends Biochem Sci       Date:  2011-07-07       Impact factor: 13.807

5.  Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function.

Authors:  Wael M Rabeh; Florian Bossard; Haijin Xu; Tsukasa Okiyoneda; Miklos Bagdany; Cory M Mulvihill; Kai Du; Salvatore di Bernardo; Yuhong Liu; Lars Konermann; Ariel Roldan; Gergely L Lukacs
Journal:  Cell       Date:  2012-01-20       Impact factor: 41.582

6.  Requirements for efficient correction of ΔF508 CFTR revealed by analyses of evolved sequences.

Authors:  Juan L Mendoza; André Schmidt; Qin Li; Emmanuel Nuvaga; Tyler Barrett; Robert J Bridges; Andrew P Feranchak; Chad A Brautigam; Philip J Thomas
Journal:  Cell       Date:  2012-01-20       Impact factor: 41.582

Review 7.  Protein quality control in the ER: balancing the ubiquitin checkbook.

Authors:  Jasper H L Claessen; Lenka Kundrat; Hidde L Ploegh
Journal:  Trends Cell Biol       Date:  2011-11-03       Impact factor: 20.808

8.  Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum.

Authors:  Ethan J Greenblatt; James A Olzmann; Ron R Kopito
Journal:  Nat Struct Mol Biol       Date:  2011-09-11       Impact factor: 15.369

9.  Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.

Authors:  Fredrick Van Goor; Sabine Hadida; Peter D J Grootenhuis; Bill Burton; Jeffrey H Stack; Kimberly S Straley; Caroline J Decker; Mark Miller; Jason McCartney; Eric R Olson; Jeffrey J Wine; Ray A Frizzell; Melissa Ashlock; Paul A Negulescu
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-05       Impact factor: 11.205

10.  Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.

Authors:  Efrat Ron; Marina Shenkman; Bella Groisman; Yana Izenshtein; Julia Leitman; Gerardo Z Lederkremer
Journal:  Mol Biol Cell       Date:  2011-09-14       Impact factor: 4.138

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  172 in total

1.  Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR.

Authors:  Scott A Houck; Hong Yu Ren; Victoria J Madden; Jacob N Bonner; Michael P Conlin; Jo Ann Janovick; P Michael Conn; Douglas M Cyr
Journal:  Mol Cell       Date:  2014-03-27       Impact factor: 17.970

2.  Arsenic Compromises Both p97 and Proteasome Functions.

Authors:  Joseph Tillotson; Christopher J Zerio; Bryan Harder; Andrew J Ambrose; Kevin S Jung; MinJin Kang; Donna D Zhang; Eli Chapman
Journal:  Chem Res Toxicol       Date:  2017-07-07       Impact factor: 3.739

3.  Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane.

Authors:  Martin Mehnert; Thomas Sommer; Ernst Jarosch
Journal:  Nat Cell Biol       Date:  2013-12-01       Impact factor: 28.824

4.  Proteome-wide measurement of protein half-lives and translation rates in vasopressin-sensitive collecting duct cells.

Authors:  Pablo C Sandoval; Dane H Slentz; Trairak Pisitkun; Fahad Saeed; Jason D Hoffert; Mark A Knepper
Journal:  J Am Soc Nephrol       Date:  2013-09-12       Impact factor: 10.121

5.  Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.

Authors:  Shengyi Sun; Guojun Shi; Xuemei Han; Adam B Francisco; Yewei Ji; Nuno Mendonça; Xiaojing Liu; Jason W Locasale; Kenneth W Simpson; Gerald E Duhamel; Sander Kersten; John R Yates; Qiaoming Long; Ling Qi
Journal:  Proc Natl Acad Sci U S A       Date:  2014-01-22       Impact factor: 11.205

6.  Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway.

Authors:  Andrey L Karamyshev; Anna E Patrick; Zemfira N Karamysheva; Dustin S Griesemer; Henry Hudson; Sandra Tjon-Kon-Sang; IngMarie Nilsson; Hendrik Otto; Qinghua Liu; Sabine Rospert; Gunnar von Heijne; Arthur E Johnson; Philip J Thomas
Journal:  Cell       Date:  2014-01-16       Impact factor: 41.582

Review 7.  Snapshot: implications for melatonin in endoplasmic reticulum homeostasis.

Authors:  Wei Hu; Zhiqiang Ma; Shouyin Di; Shuai Jiang; Yue Li; Chongxi Fan; Yang Yang; Dongjin Wang
Journal:  Br J Pharmacol       Date:  2016-11-16       Impact factor: 8.739

8.  The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein.

Authors:  Satoshi Horimoto; Satoshi Ninagawa; Tetsuya Okada; Hibiki Koba; Takehiro Sugimoto; Yukiko Kamiya; Koichi Kato; Shunichi Takeda; Kazutoshi Mori
Journal:  J Biol Chem       Date:  2013-09-16       Impact factor: 5.157

Review 9.  Sorting out the trash: the spatial nature of eukaryotic protein quality control.

Authors:  Emily Mitchell Sontag; Willianne I M Vonk; Judith Frydman
Journal:  Curr Opin Cell Biol       Date:  2014-01-23       Impact factor: 8.382

10.  Role for Lipid Droplet Biogenesis and Microlipophagy in Adaptation to Lipid Imbalance in Yeast.

Authors:  Jason D Vevea; Enrique J Garcia; Robin B Chan; Bowen Zhou; Mei Schultz; Gilbert Di Paolo; J Michael McCaffery; Liza A Pon
Journal:  Dev Cell       Date:  2015-12-07       Impact factor: 12.270

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