| Literature DB >> 23217417 |
Agnieszka I Laskowski1, Paul S Knoepfler.
Abstract
Recently in Cell, Jia et al. (2012) reported novel Utf1-controlled mechanisms of maintaining pluripotency and self-renewal in embryonic stem cells (ESCs). Utf1 buffers bivalent gene expression by competitive binding with polycomb repressive complex 2 and initiation of mRNA degradation.Entities:
Year: 2012 PMID: 23217417 PMCID: PMC3684620 DOI: 10.1016/j.stem.2012.11.012
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633