Literature DB >> 23215718

Potential value and limitation of dual inhibitors of PI3K and mTOR in the treatment of cancer.

Jiezhong Chen.   

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Year:  2013        PMID: 23215718     DOI: 10.2174/1568009611313020001

Source DB:  PubMed          Journal:  Curr Cancer Drug Targets        ISSN: 1568-0096            Impact factor:   3.428


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  6 in total

1.  PUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancer.

Authors:  Huanan Wang; Lingling Zhang; Xu Yang; Yipeng Jin; Shimin Pei; Di Zhang; Hong Zhang; Bin Zhou; Yingjie Zhang; Degui Lin
Journal:  Oncotarget       Date:  2015-06-10

2.  Acquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance.

Authors:  L Chang; P H Graham; J Hao; J Ni; J Bucci; P J Cozzi; J H Kearsley; Y Li
Journal:  Cell Death Dis       Date:  2013-10-24       Impact factor: 8.469

Review 3.  Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells.

Authors:  Valdenizia R Silva; Luciano de S Santos; Rosane B Dias; Claudio A Quadros; Daniel P Bezerra
Journal:  Cancer Commun (Lond)       Date:  2021-11-17

4.  Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways.

Authors:  Jiezhong Chen; Renfu Shao; Li Li; Zhi Ping Xu; Wenyi Gu
Journal:  Int J Nanomedicine       Date:  2014-07-16

5.  Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis.

Authors:  Hong Zou; Li Li; Ines Garcia Carcedo; Zhi Ping Xu; Michael Monteiro; Wenyi Gu
Journal:  Int J Nanomedicine       Date:  2016-05-05

6.  Targeted inhibition of the phosphoinositide 3-kinase impairs cell proliferation, survival, and invasion in colon cancer.

Authors:  Fei Yang; Jun-Yi Gao; Hua Chen; Zhen-Hua Du; Xue-Qun Zhang; Wei Gao
Journal:  Onco Targets Ther       Date:  2017-09-11       Impact factor: 4.147

  6 in total

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