Literature DB >> 23215010

Optical methods for single molecule detection and analysis.

David R Walt1.   

Abstract

As analytical chemists, the highest resolution measurement one can make is at the single molecule level; it just does not get any better than that. To determine the concentration of a molecule in solution, the best way is to count the number of molecules in a given volume. As long as the volume contains a statistically large enough number of molecules and is above the Poisson noise limit, molecular counting is the most accurate way to make a measurement. Molecular counting is the method of the future and is beginning to be performed today.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 23215010      PMCID： PMC3565068          DOI： 10.1021/ac3027178

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  19 in total

1.  Digital PCR.

Authors:  B Vogelstein; K W Kinzler
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

2.  Single-target molecule detection with nonbleaching multicolor optical immunolabels.

Authors:  S Schultz; D R Smith; J J Mock; D A Schultz
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-01       Impact factor: 11.205

3.  Sequence information can be obtained from single DNA molecules.

Authors:  Ido Braslavsky; Benedict Hebert; Emil Kartalov; Stephen R Quake
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-21       Impact factor: 11.205

4.  Zero-mode waveguides for single-molecule analysis at high concentrations.

Authors:  M J Levene; J Korlach; S W Turner; M Foquet; H G Craighead; W W Webb
Journal:  Science       Date:  2003-01-31       Impact factor: 47.728

5.  Microfluidic digital PCR enables multigene analysis of individual environmental bacteria.

Authors:  Elizabeth A Ottesen; Jong Wook Hong; Stephen R Quake; Jared R Leadbetter
Journal:  Science       Date:  2006-12-01       Impact factor: 47.728

6.  Label-free, single-molecule detection with optical microcavities.

Authors:  Andrea M Armani; Rajan P Kulkarni; Scott E Fraser; Richard C Flagan; Kerry J Vahala
Journal:  Science       Date:  2007-07-05       Impact factor: 47.728

7.  Detection of single-molecule DNA hybridization using enzymatic amplification in an array of femtoliter-sized reaction vessels.

Authors:  Zhaohui Li; Ryan B Hayman; David R Walt
Journal:  J Am Chem Soc       Date:  2008-09-03       Impact factor: 15.419

Review 8.  A practical guide to single-molecule FRET.

Authors:  Rahul Roy; Sungchul Hohng; Taekjip Ha
Journal:  Nat Methods       Date:  2008-06       Impact factor: 28.547

9.  Identifying secretomes in people, pufferfish and pigs.

Authors:  Eric W Klee; Daniel F Carlson; Scott C Fahrenkrug; Stephen C Ekker; Lynda B M Ellis
Journal:  Nucleic Acids Res       Date:  2004-02-27       Impact factor: 16.971

10.  Probing cellular protein complexes using single-molecule pull-down.

Authors:  Ankur Jain; Ruijie Liu; Biswarathan Ramani; Edwin Arauz; Yuji Ishitsuka; Kaushik Ragunathan; Jeehae Park; Jie Chen; Yang K Xiang; Taekjip Ha
Journal:  Nature       Date:  2011-05-26       Impact factor: 49.962
View more
  32 in total

1.  Expanding the Dynamic Range of Fluorescence Assays through Single-Molecule Counting and Intensity Calibration.

Authors:  Lucas Smith; Manish Kohli; Andrew M Smith
Journal:  J Am Chem Soc       Date:  2018-10-12       Impact factor: 15.419

2.  A Bayesian Nonparametric Approach to Single Molecule Förster Resonance Energy Transfer.

Authors:  Ioannis Sgouralis; Shreya Madaan; Franky Djutanta; Rachael Kha; Rizal F Hariadi; Steve Pressé
Journal:  J Phys Chem B       Date:  2019-01-10       Impact factor: 2.991

Review 3.  Rare cell isolation and analysis in microfluidics.

Authors:  Yuchao Chen; Peng Li; Po-Hsun Huang; Yuliang Xie; John D Mai; Lin Wang; Nam-Trung Nguyen; Tony Jun Huang
Journal:  Lab Chip       Date:  2014-02-21       Impact factor: 6.799

Review 4.  Emerging technologies to increase ligand binding assay sensitivity.

Authors:  Saloumeh K Fischer; Alison Joyce; Mark Spengler; Tong-Yuan Yang; Yao Zhuang; Marianne Scheel Fjording; Alvydas Mikulskis
Journal:  AAPS J       Date:  2014-10-18       Impact factor: 4.009

5.  Direct single-molecule imaging for diagnostic and blood screening assays.

Authors:  Qiaoqiao Ruan; Patrick J Macdonald; Kerry M Swift; Sergey Y Tetin
Journal:  Proc Natl Acad Sci U S A       Date:  2021-04-06       Impact factor: 11.205

6.  Recent advances in the analysis of therapeutic proteins by capillary and microchip electrophoresis.

Authors:  Jessica S Creamer; Nathan J Oborny; Susan M Lunte
Journal:  Anal Methods       Date:  2014-07-08       Impact factor: 2.896

7.  Miniaturized, multiplexed readout of droplet-based microfluidic assays using time-domain modulation.

Authors:  Melaku Muluneh; Bawul Kim; Gershon Buchsbaum; David Issadore
Journal:  Lab Chip       Date:  2014-10-14       Impact factor: 6.799

Review 8.  Critical Review: digital resolution biomolecular sensing for diagnostics and life science research.

Authors:  Qinglan Huang; Nantao Li; Hanyuan Zhang; Congnyu Che; Fu Sun; Yanyu Xiong; Taylor D Canady; Brian T Cunningham
Journal:  Lab Chip       Date:  2020-07-23       Impact factor: 6.799

9.  Ensemble Sensing Using Single-Molecule DNA Copolymers.

Authors:  Sagun Jonchhe; Sangeetha Selvam; Deepak Karna; Shankar Mandal; Benjamin Wales-McGrath; Hanbin Mao
Journal:  Anal Chem       Date:  2020-09-08       Impact factor: 6.986

Review 10.  Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease.

Authors:  J Gustav Smith; Robert E Gerszten
Journal:  Circulation       Date:  2017-04-25       Impact factor: 29.690
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.