Literature DB >> 23214502

Pd-catalyzed β-selective direct C-H bond arylation of thiophenes with aryltrimethylsilanes.

Kenji Funaki1, Tetsuo Sato, Shuichi Oi.   

Abstract

Direct arylation of thiophenes and benzothiophenes with aryltrimethylsilanes was effectively catalyzed by PdCl(2)(MeCN)(2) in the presence of CuCl(2) as an oxidant. The reaction preferentially occurred at the β-position of both thiophenes and benzothiophenes.

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Year:  2012        PMID： 23214502     DOI： 10.1021/ol3029109

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Direct Vicinal Difunctionalization of Thiophenes Enabled by the Palladium/Norbornene Cooperative Catalysis.

Authors:  Renhe Li; Yun Zhou; Xiaolong Xu; Guangbin Dong
Journal:  J Am Chem Soc       Date:  2019-11-22       Impact factor: 15.419

2.  Room-Temperature Direct β-Arylation of Thiophenes and Benzo[b]thiophenes and Kinetic Evidence for a Heck-type Pathway.

Authors:  Chiara Colletto; Saidul Islam; Francisco Juliá-Hernández; Igor Larrosa
Journal:  J Am Chem Soc       Date:  2016-01-28       Impact factor: 15.419

3.  Regioselective synthesis of C3 alkylated and arylated benzothiophenes.

Authors:  Harry J Shrives; José A Fernández-Salas; Christin Hedtke; Alexander P Pulis; David J Procter
Journal:  Nat Commun       Date:  2017-03-20       Impact factor: 14.919

4.  Direct synthesis and applications of solid silylzinc reagents.

Authors:  Revathi Chandrasekaran; Feba Thomas Pulikkottil; Krishna Suresh Elama; Ramesh Rasappan
Journal:  Chem Sci       Date:  2021-11-30       Impact factor: 9.825

5.  Defluorosilylation of fluoroarenes and fluoroalkanes.

Authors:  Benqiang Cui; Shichong Jia; Etsuko Tokunaga; Norio Shibata
Journal:  Nat Commun       Date:  2018-10-22       Impact factor: 14.919
  5 in total

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