PURPOSE: To establish if preoperative arterial blood lactate (Lac) is a factor related to hospital death for patients with a ruptured abdominal aortic aneurysm (rAAA). METHODS: The subjects were 55 patients who underwent surgery for an rAAA in a single institution between July, 2000 and November, 2009. Patients were divided into a survivor group and a non-survivor group. We compared the preoperative Lac levels and other data between the groups. RESULTS: There were ten hospital deaths. On univariate analysis, preoperative Lac levels, shock vital, cardiopulmonary resuscitation, Hardman index ≥3, and Glasgow aneurysm score ≥84 were significantly higher and preoperative hemoglobin was significantly lower in the non-survivor group. The postoperative mortality rate tended to increase with preoperative Lac levels. The mortality rate of patients with a preoperative Lac level higher than 9 mmol/l was 86 %. Those factors that had significant association with hospital mortality on univariate analysis were consecutively analyzed using multivariate logistic regression analysis. The multivariate logistic regression analysis revealed that a preoperative Lac level >9 mmol/l was the only independent risk factor of hospital mortality. CONCLUSION: The preoperative Lac level of patients with a rAAA may be a predictor of their prognosis.
PURPOSE: To establish if preoperative arterial blood lactate (Lac) is a factor related to hospital death for patients with a ruptured abdominal aortic aneurysm (rAAA). METHODS: The subjects were 55 patients who underwent surgery for an rAAA in a single institution between July, 2000 and November, 2009. Patients were divided into a survivor group and a non-survivor group. We compared the preoperative Lac levels and other data between the groups. RESULTS: There were ten hospital deaths. On univariate analysis, preoperative Lac levels, shock vital, cardiopulmonary resuscitation, Hardman index ≥3, and Glasgow aneurysm score ≥84 were significantly higher and preoperative hemoglobin was significantly lower in the non-survivor group. The postoperative mortality rate tended to increase with preoperative Lac levels. The mortality rate of patients with a preoperative Lac level higher than 9 mmol/l was 86 %. Those factors that had significant association with hospital mortality on univariate analysis were consecutively analyzed using multivariate logistic regression analysis. The multivariate logistic regression analysis revealed that a preoperative Lac level >9 mmol/l was the only independent risk factor of hospital mortality. CONCLUSION: The preoperative Lac level of patients with a rAAA may be a predictor of their prognosis.
Authors: Marcel Gatt; Paul Goldsmith; Marcos Martinez; Jesus Barandiaran; Kartikae Grover; Naif El-Barghouti; Eugene P Perry Journal: Ann R Coll Surg Engl Date: 2008-12-19 Impact factor: 1.891
Authors: Houman Khosravani; Reza Shahpori; H Thomas Stelfox; Andrew W Kirkpatrick; Kevin B Laupland Journal: Crit Care Date: 2009-06-12 Impact factor: 9.097