Pasting together the preventive therapy puzzle.

In children, the effectiveness of preventive therapy (PT) for tuberculosis (TB) will always be dependent upon the care giver's behaviour, as this determines adherence. We briefly describe the knowledge, attitudes and intended behaviours in care givers of young children referred for PT in a resource-constrained setting with high TB rates. These early efforts describe one critical piece of the PT puzzle: uptake. More behavioural research is needed to understand how the many pieces of this puzzle should be assembled to improve PT usage in children.