Objective: Seborrheic dermatitis (SD) is commonly treated with anti-inflammatory products, including topical corticosteroids. This study was undertaken to compare the efficiency of sertaconazole 2% cream with hydrocortisone 1% cream in the treatment of SD. Methods: In this clinical trial study, 60 SD patients were studied. Thirty patients received local sertaconazole 2% cream and were recommended to use the cream twice a day for 4 weeks. In the control group, 30 patients received hydrocortisone 1% cream and were recommended to use the cream twice a day for 4 weeks. At the start of the study and also 2 and 4 weeks after first visit, the patients were examined by a dermatologist for signs of improvement and control of clinical symptoms. Results: The mean age of the patients was 32.23 ± 12.09. The highest level of satisfaction (90%) was observed 28 days after using sertaconazole and the level of satisfaction was 83.3% in hydrocortisone group. Relapse of the disease one month after stopping treatment was not observed in both groups treated with sertaconazole 2% cream and hydrocortisone 1% cream. Conclusion:Topical sertaconazole therapy is a considerable advancement in the treatment of SD with corticosteroids. The cure rate was somewhat higher in the sertaconazole group and it can be considered as the nonsteroidal alternative to topical steroid therapy for SD.
RCT Entities:
Objective: Seborrheic dermatitis (SD) is commonly treated with anti-inflammatory products, including topical corticosteroids. This study was undertaken to compare the efficiency of sertaconazole 2% cream with hydrocortisone 1% cream in the treatment of SD. Methods: In this clinical trial study, 60 SDpatients were studied. Thirty patients received local sertaconazole 2% cream and were recommended to use the cream twice a day for 4 weeks. In the control group, 30 patients received hydrocortisone 1% cream and were recommended to use the cream twice a day for 4 weeks. At the start of the study and also 2 and 4 weeks after first visit, the patients were examined by a dermatologist for signs of improvement and control of clinical symptoms. Results: The mean age of the patients was 32.23 ± 12.09. The highest level of satisfaction (90%) was observed 28 days after using sertaconazole and the level of satisfaction was 83.3% in hydrocortisone group. Relapse of the disease one month after stopping treatment was not observed in both groups treated with sertaconazole 2% cream and hydrocortisone 1% cream. Conclusion: Topical sertaconazole therapy is a considerable advancement in the treatment of SD with corticosteroids. The cure rate was somewhat higher in the sertaconazole group and it can be considered as the nonsteroidal alternative to topical steroid therapy for SD.