Literature DB >> 23207755

Histological aspects of autologous transplantation of different fragments of the spleen in rats.

Ana Abreu Braga1, Rodolfo Malagó, Thiago Pires Anacleto, Cristiano Rodrigo Nicomedes da Silva, Nelson Adami Andreollo, Fabio Luis Figueiredo Fernandes.   

Abstract

PURPOSE: To evaluate macro and microscopically the evolution of autotransplants of fragments of spleen different fragments in the greater omentum, after eight weeks of observation.
METHODS: Twenty rats Wistar were used, males and adults, submitted to total splenectomy and divided in two groups. The group I - ten animals with implant of spleen fragment (25% weight of spleen) in the omentum; and group II - ten animals with implant of spleen fragment (30% weight of spleen) in the omentum. It was analyzed macro and microscopically the evolution of the implant.
RESULTS: It was observed adherences to the adjacent tissues and vascularization in all of the fragments transplanted. The group I and II presented white pulp with follicular formations and lymphoid tissue preserved, and the red pulp in cordon aspect. The group II presented white pulp more disorganized and red pulp hemorrhagic. The active macrophages were observed in the group I and II.
CONCLUSION: The splenic autotransplantation of the group I showed better regeneration.

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Year:  2012        PMID: 23207755     DOI: 10.1590/s0102-86502012001200009

Source DB:  PubMed          Journal:  Acta Cir Bras        ISSN: 0102-8650            Impact factor:   1.388


  2 in total

1.  INFLUENCE OF SPLENIC IMPLANTS IN THE SUBCUTANEOUS TISSUE ON ASPLENIC ANIMALS SURVIVAL.

Authors:  Renan Kleber Costa Teixeira; Laryssa de Aquino Santiago; Yan de Assis Sasaki; Vitor Nagai Yamaki; Daniel Haber Feijó; Marcus Vinicius Henriques Brito; Edson Yuzur Yasojima; Andy Petroianu
Journal:  Arq Bras Cir Dig       Date:  2018-07-02

Review 2.  Spleen: Reparative Regeneration and Influence on Liver.

Authors:  Andrey Elchaninov; Polina Vishnyakova; Gennady Sukhikh; Timur Fatkhudinov
Journal:  Life (Basel)       Date:  2022-04-22
  2 in total

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