Literature DB >> 2320717

Gangliosides enhance the anti-immobility response elicited by several antidepressant treatments in mice.

N E Córdoba1, A M Basso, V A Molina, O A Orsingher.   

Abstract

Ganglioside pretreatment enhanced the anti-immobility effect induced in the forced swim test after a chronic treatment with desipramine, mianserin, clomipramine, nialamide or repeated electroconvulsive shock in mice. Gangliosides, which had no effect per se, showed a clear dose-response relationship in enhancing the anti-immobility effect of desipramine. These results suggest that, regardless of their mechanisms of action, gangliosides facilitate the behavioral response of several antidepressant treatments.

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Year:  1990        PMID： 2320717     DOI： 10.1007/bf02244011

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  7 in total

1.  Development of beta-adrenergic receptor subsensitivity by antidepressants.

Authors:  S P Banerjee; L S Kung; S J Riggi; S K Chanda
Journal:  Nature       Date:  1977-08-04       Impact factor: 49.962

2.  A possible common mechanism of action of antidepressant treatments: reduction in the sensitivity of the noradrenergic cyclic AMP gererating system in the rat limbic forebrain.

Authors:  J Vetulani; R J Stawarz; J V Dingell; F Sulser
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-05       Impact factor: 3.000

3.  Gangliosides enhance behavioral and neurochemical effects induced by chronic desipramine (DMI) treatment.

Authors:  V A Molina; E A Keller; O A Orsingher
Journal:  Eur J Pharmacol       Date:  1989-01-31       Impact factor: 4.432

Review 4.  Biology of gangliosides: neuritogenic and neuronotrophic properties.

Authors:  R W Ledeen
Journal:  J Neurosci Res       Date:  1984       Impact factor: 4.164

5.  Behavioral despair in mice: a primary screening test for antidepressants.

Authors:  R D Porsolt; A Bertin; M Jalfre
Journal:  Arch Int Pharmacodyn Ther       Date:  1977-10

6.  Phospholipid liposomes potentiate the inhibitory effect of antidepressant drugs on immobility of rats in a despair test (constrained swim).

Authors:  F Drago; G Continella; G A Mason; D E Hernandez; U Scapagnini
Journal:  Eur J Pharmacol       Date:  1985-09-24       Impact factor: 4.432

7.  The functional recovery of damaged brain: the effect of GM1 monosialoganglioside.

Authors:  G Toffano; G Savoini; F Aporti; S Calzolari; A Consolazione; G Maura; M Marchi; M Raiteri; L F Agnati
Journal:  J Neurosci Res       Date:  1984       Impact factor: 4.164
  7 in total
  1 in total

1.  Antidepressant-Like Effects of GM1 Ganglioside Involving the BDNF Signaling Cascade in Mice.

Authors:  Bo Jiang; Lu Song; Cheng-Niu Wang; Wei Zhang; Chao Huang; Li-Juan Tong
Journal:  Int J Neuropsychopharmacol       Date:  2016-09-21       Impact factor: 5.176
  1 in total

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