Literature DB >> 23204697

Surgical Indications for Goiter with Background Hashimoto's Thyroiditis: Institutional Experience.

P R K Bhargav1, S Shekhar.   

Abstract

Hashimoto's thyroiditis (HT) is usually treated conservatively with thyroxine. Its incidence is higher in Iodine sufficient areas and may require surgery for associated nodularity or complications. A retrospective study on surgically treated HT cases was conducted in a teritiary care teaching hospital in an Iodine sufficient area of Southern India. 34 cases of goiter with associated HT, who underwent thyroidectomy between 2007 and 2010 were analysed for indications of surgery. Minimum follow-up period was 6 months. F:M ratio was 31:3 with mean age of 41.3 years. Goiter was diffuse in 41% and nodular in 59%. 16 (47%) of patients were hypothyroid. Autoimmune association was found in 35%. Commonest surgery done was hemithyroidectomy in 12 (35%) followed by subtotal thyroidectomy in 10 cases. Most frequent indication for surgery was nodular goiter in 12 (35%) followed by associated malignancy, persistent goiter, pressure symptoms and painful thyroiditis. Histopathology showed diffuse HT alone in 12 (35%) and rest of the cases had HT as a component synchronous with other pathologies. Associated pathologies were benign multinodular goiter (6), colloid nodule (6), papillary cancer (5), follicular adenoma (4), cyst (1). Surgery for HT is primarily indicated for associated pathologies like dominant nodule, suspicious or proven malignancy, persistent goiter, painful thyroiditis, pressure symptoms and rarely for HT perse. Rate of surgery for HT associated goiter appears to be higher in Iodine sufficient areas, the cause of which needs to be studied further.

Entities:  

Keywords:  Hashimoto’s thyroiditis; Surgery; Thyroxine

Year:  2011        PMID: 23204697      PMCID: PMC3236274          DOI: 10.1007/s12262-011-0344-0

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  24 in total

Review 1.  Coexisting Hashimoto's thyroiditis with differentiated thyroid cancer and benign thyroid diseases: indications for thyroidectomy.

Authors:  Adolfo Pisanu; Sara Piu; Alessandro Cois; Alessandro Uccheddu
Journal:  Chir Ital       Date:  2003 May-Jun

2.  Riedel's thyroiditis and fibrous variant of Hashimoto's thyroiditis: a clinicopathological and immunohistochemical study.

Authors:  G Papi; S Corrado; C Carapezzi; C De Gaetani; C Carani
Journal:  J Endocrinol Invest       Date:  2003-05       Impact factor: 4.256

3.  Chronic lymphocytic (Hashimoto's) thyroiditis in Kuwait diagnosed by fine needle aspirates.

Authors:  K Kapila; S A Sathar; N A Al-Rabah; A Prahash; M S Seshadri
Journal:  Ann Saudi Med       Date:  1995-07       Impact factor: 1.526

4.  Hashimoto's thyroiditis simulating De Quervain's thyroiditis.

Authors:  A K Leung; K Hegde
Journal:  J Adolesc Health Care       Date:  1988-09

5.  Hashimoto's thyroiditis and thyroid cancer: indications for operation.

Authors:  O H Clark; F S Greenspan; J E Dunphy
Journal:  Am J Surg       Date:  1980-07       Impact factor: 2.565

6.  Painful Hashimoto's thyroiditis as an indication for thyroidectomy: clinical characteristics and outcome in seven patients.

Authors:  Yin C Kon; Leslie J DeGroot
Journal:  J Clin Endocrinol Metab       Date:  2003-06       Impact factor: 5.958

7.  Cancer risks in patients with chronic lymphocytic thyroiditis.

Authors:  L E Holm; H Blomgren; T Löwhagen
Journal:  N Engl J Med       Date:  1985-03-07       Impact factor: 91.245

Review 8.  Thyroiditis. Acute, subacute, and chronic.

Authors:  P A Singer
Journal:  Med Clin North Am       Date:  1991-01       Impact factor: 5.456

9.  Surgical intervention in chronic (Hashimoto's) thyroiditis.

Authors:  C G Thomas; R G Rutledge
Journal:  Ann Surg       Date:  1981-06       Impact factor: 12.969

10.  Lymphocytic thyroiditis--is cytological grading significant? A correlation of grades with clinical, biochemical, ultrasonographic and radionuclide parameters.

Authors:  Alka Bhatia; Arvind Rajwanshi; Radharaman J Dash; Bhagwant R Mittal; Akshay K Saxena
Journal:  Cytojournal       Date:  2007-04-30       Impact factor: 2.091

View more
  4 in total

1.  Identifying predictors of a difficult thyroidectomy.

Authors:  Valerie M Mok; Sarah C Oltmann; Herbert Chen; Rebecca S Sippel; David F Schneider
Journal:  J Surg Res       Date:  2014-03-19       Impact factor: 2.192

2.  Risk factors for difficult thyroidectomy and postoperative morbidity do not match: retrospective study from an endocrine surgery academic referral centre.

Authors:  F P Prete; P C Panzera; G Di Meo; A Pasculli; L I Sgaramella; G Calculli; R Dimonte; F Ferrarese; M Testini; A Gurrado
Journal:  Updates Surg       Date:  2022-09-05

3.  Antithyroid Peroxidase Antibodies in Multinodular Hashimoto's Thyroiditis Indicate a Variant Etiology.

Authors:  Pabithadevi B Mehanathan; R Raskin Erusan; K Shantaraman; S M Kannan
Journal:  J Thyroid Res       Date:  2019-07-21

4.  Giant cervical goiter in Hashimoto's thyroiditis: A case report.

Authors:  Tang Tao; Yang Gang; Sun Ji; Chen Xiao-Li; Li Wei-Nan; Li Qiang; Zhu Jian-Jiao; Xiong Yong-Fu; Li Jing-Dong
Journal:  J Int Med Res       Date:  2022-05       Impact factor: 1.671

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.