Literature DB >> 23204689

A Paradigm Shift in the Epidemiology of HIV in Pregnancy at ICTC of a Medical College.

Sudarsan Saha1, Rupkamal Das, Soma Saha, Arunangshu De, Mayoukh Chakraborty, Sumanta Kumar Mandal.   

Abstract

OBJECTIVES: To study the present status and effect of paradigm shift in the epidemiology of HIV amongst pregnant women in urban set up. AIMS: The purpose of the study is to evaluate the paradigm shift in overall screening and management strategy of HIV in antenatal women for last four and half years in an urban medical college.
METHODS: The study was conducted from 1st January 2004 to 30th June 2008 and all registered and unregistered pregnant women who attended ICTC clinic and also for emergency admission (unregistered) were counseled and blood samples were tested as per NACO guidelines with cafeteria choice of opt in and opt out strategy. Reactive women in antenatal period were counseled and discussed about anti-retroviral therapy (ART) and universal treatment regime. Seroprevalent women were counseled about their spouse, personal habits and demographic status. Marked improvement was seen in the use of contraceptive and drug abuse. During labor mother and baby were given nevirapine as per NACO guidelines.
RESULTS: The seroprevalence of HIV reactive women in our Centre was 0.23, 0.19, 0.14 and 0.12% in the year 2004, 2005, 2006, 2007 and zero prevalence in 2008 till date. Spouse positivity was noted in 80, 58.33, 72.72 and 70% in the set period from 2004 to 2008.
CONCLUSION: Marked improvement was noticed in all the strategic points from registration, counseling, screening and availability of improved diagnostic kits for screening HIV 1 and HIV 2.

Entities:  

Keywords:  Integrated Counseling and Testing Centre (ICTC); Paradigm shift

Year:  2012        PMID: 23204689      PMCID: PMC3307922          DOI: 10.1007/s13224-011-0108-6

Source DB:  PubMed          Journal:  J Obstet Gynaecol India        ISSN: 0975-6434


  4 in total

1.  Guidelines for the management of HIV infection in pregnant women and the prevention of mother-to-child transmission.

Authors:  E G Lyall; M Blott; A de Ruiter; D Hawkins; D Mercy; Z Mitchla; M L Newell; S O'Shea; J R Smith; J Sunderland; R Webb; G P Taylor
Journal:  HIV Med       Date:  2001-10       Impact factor: 3.180

2.  Strategy for preventing vertical transmisssion of HIV : Bombay experience.

Authors:  R H Merchant; K Damania; I S Gilada; R V Bhagwat; J S Karkare; J S Oswal; S R Merchant; S Changedia
Journal:  Indian Pediatr       Date:  2001-02       Impact factor: 1.411

3.  Efficacy of three short-course regimens of zidovudine and lamivudine in preventing early and late transmission of HIV-1 from mother to child in Tanzania, South Africa, and Uganda (Petra study): a randomised, double-blind, placebo-controlled trial.

Authors: 
Journal:  Lancet       Date:  2002-04-06       Impact factor: 79.321

4.  Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial.

Authors:  L A Guay; P Musoke; T Fleming; D Bagenda; M Allen; C Nakabiito; J Sherman; P Bakaki; C Ducar; M Deseyve; L Emel; M Mirochnick; M G Fowler; L Mofenson; P Miotti; K Dransfield; D Bray; F Mmiro; J B Jackson
Journal:  Lancet       Date:  1999-09-04       Impact factor: 79.321

  4 in total

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