OBJECTIVES: To correlate the severity of the disease, maternal and perinatal outcome with Lactic Dehydrogenase (LDH) levels in serum in patients of preeclampsia and eclampsia. METHODS: A prospective comparative study was conducted in the department of Obstetrics and Gynecology in the collaboration with department of Pathology, CSM Medical University, Lucknow. Out of 146 women studied, 39 were normal pregnant women, 35 were of mild preeclampsia, 36 of severe preeclampsia and 36 of eclampsia. The statistical analysis was done by Chi-square test (for proportional data) analysis of variance and sample "t" test (for parametric data). RESULTS: LDH levels were significantly elevated in women with preeclampsia and eclampsia (<0.001). Higher LDH levels had significant correlation with high blood pressure (P < 0.10) as well as poor maternal and perinatal outcome. CONCLUSION: High serum LDH levels correlate well with the severity of the disease and poor outcomes in patients of preeclampsia and eclampsia.
OBJECTIVES: To correlate the severity of the disease, maternal and perinatal outcome with Lactic Dehydrogenase (LDH) levels in serum in patients of preeclampsia and eclampsia. METHODS: A prospective comparative study was conducted in the department of Obstetrics and Gynecology in the collaboration with department of Pathology, CSM Medical University, Lucknow. Out of 146 women studied, 39 were normal pregnant women, 35 were of mild preeclampsia, 36 of severe preeclampsia and 36 of eclampsia. The statistical analysis was done by Chi-square test (for proportional data) analysis of variance and sample "t" test (for parametric data). RESULTS: LDH levels were significantly elevated in women with preeclampsia and eclampsia (<0.001). Higher LDH levels had significant correlation with high blood pressure (P < 0.10) as well as poor maternal and perinatal outcome. CONCLUSION: High serum LDH levels correlate well with the severity of the disease and poor outcomes in patients of preeclampsia and eclampsia.
Authors: S Cansun Demir; Cuneyt Evruke; Fatma T Ozgunen; Ibrahim F Urunsak; Erdal Candan; Oktay Kadayifci Journal: Saudi Med J Date: 2006-07 Impact factor: 1.484
Authors: V A Catanzarite; S M Steinberg; C A Mosley; C F Landers; L M Cousins; J M Schneider Journal: Am J Perinatol Date: 1995-09 Impact factor: 1.862
Authors: V Junewar; R Verma; P L Sankhwar; R K Garg; M K Singh; H S Malhotra; P K Sharma; A Parihar Journal: AJNR Am J Neuroradiol Date: 2014-04-10 Impact factor: 3.825