Literature DB >> 2320416

Transcription factor USF from duck erythrocytes transactivates expression of the histone H5 gene in vitro by interacting with an intragenic sequence.

F Düring1, H Gerhold, K H Seifart.   

Abstract

The duck histone H5 gene contains a 12 base pair (bp) sequence motif within the coding region, which shows homology in 10 out of 12 bp with the consensus sequence of the USF binding site in the Ad2ML-promoter. The functional equivalent of transcription factor USF, partially purified from whole cell extracts of duck erythrocytes (EUSF), was shown to interact with this intragenic sequence. Electrophoretic mobility shift analyses revealed the selective formation of a complex between this protein fraction and the duck H5 gene. Footprint assays with DNase I delineated specific binding to the intragenic sequence outlined above. Moreover this protein fraction, containing EUSF, transactivates the expression of the duck H5 gene in vitro and elimination of the USF-consensus sequence leads to a loss of stimulation but retains the basic transcription of the gene. These results suggest an as yet unknown functional role of EUSF in the expression of the H5 gene of the duck.

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Year:  1990        PMID： 2320416      PMCID： PMC330438          DOI： 10.1093/nar/18.5.1225

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  32 in total

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Authors:  K Yu; R T Elder
Journal:  Mol Cell Biol       Date:  1989-09       Impact factor: 4.272

2.  Downstream sequences affect transcription initiation from the adenovirus major late promoter.

Authors:  S L Mansour; T Grodzicker; R Tjian
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272

3.  Protein factor(s) binding independently to two different regions of the adenovirus 2 major late promoter.

Authors:  X P Shi; R Lee; R Weinmann
Journal:  Nucleic Acids Res       Date:  1986-05-12       Impact factor: 16.971

4.  An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter.

Authors:  R W Carthew; L A Chodosh; P A Sharp
Journal:  Cell       Date:  1985-12       Impact factor: 41.582

5.  Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements.

Authors:  W Lee; P Mitchell; R Tjian
Journal:  Cell       Date:  1987-06-19       Impact factor: 41.582

6.  A 3' enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult beta-globin gene.

Authors:  O R Choi; J D Engel
Journal:  Nature       Date:  1986 Oct 23-29       Impact factor: 49.962

7.  Fine analysis of the active H5 gene chromatin of chicken erythroid cells at different stages of differentiation.

Authors:  J Renaud; A Ruiz-Carrillo
Journal:  J Mol Biol       Date:  1986-05-05       Impact factor: 5.469

8.  Isolation of a Saccharomyces cerevisiae centromere DNA-binding protein, its human homolog, and its possible role as a transcription factor.

Authors:  R J Bram; R D Kornberg
Journal:  Mol Cell Biol       Date:  1987-01       Impact factor: 4.272

9.  Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

Authors:  M R Montminy; K A Sevarino; J A Wagner; G Mandel; R H Goodman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

10.  Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter.

Authors:  N G Miyamoto; V Moncollin; J M Egly; P Chambon
Journal:  EMBO J       Date:  1985-12-16       Impact factor: 11.598
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  3 in total

1.  Transcription factor IIA is inactivated during terminal differentiation of avian erythroid cells.

Authors:  J Bungert; R Waldschmidt; I Kober; K H Seifart
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

2.  Cooperation between upstream and downstream elements of the adenovirus major late promoter for maximal late phase-specific transcription.

Authors:  G Mondésert; C Kédinger
Journal:  Nucleic Acids Res       Date:  1991-06-25       Impact factor: 16.971

3.  Development of an inducible pol III transcription system essentially requiring a mutated form of the TATA-binding protein.

Authors:  W Meissner; H Rothfels; B Schäfer; K Seifart
Journal:  Nucleic Acids Res       Date:  2001-04-15       Impact factor: 16.971
  3 in total

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