| Literature DB >> 23201598 |
Vanna Sanna1, Imtiaz A Siddiqui2, Mario Sechi1, Hasan Mukhtar3.
Abstract
There is a need for developing improved therapeutic options for the management of prostate cancer, able to inhibit proliferation of precancerous and malignant lesions and/or to improve the effectiveness of conventional chemopreventive and chemotherapeutic agents. In this perspective, application of nanotechnology based strategies for the delivery of natural compounds for effective management of the disease is being actively researched. Here, after highlighting the most promising natural compounds for chemoprevention and chemotherapy of prostate cancer, the state of the art nanotherapeutics and the recent proof-of-concept of "nanochemoprevention", as well as the clinical development of promising targeted nanoprototypes for use in the prostate cancer treatment are being discussed.Entities:
Mesh:
Substances:
Year: 2012 PMID: 23201598 PMCID: PMC3890375 DOI: 10.1016/j.canlet.2012.11.037
Source DB: PubMed Journal: Cancer Lett ISSN: 0304-3835 Impact factor: 8.679