Literature DB >> 232006

Protective effect of polymyxin B sulfate in experimental enterobacterial infection in mice.

R M Bannatyne, R Cheung.   

Abstract

The mouse model of intraperitoneal enterobacterial sepsis was used to evaluate the anti-endotoxic effect of polymyxin B sulfate. Single or multiple therapeutic doses of polymyxin, administered either before or after lethal challenge with Serratia marcescens, produced statistically and clinically significant protective effects.

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Year:  1979        PMID： 232006     DOI： 10.1139/m79-153

Source DB:  PubMed          Journal:  Can J Microbiol        ISSN： 0008-4166            Impact factor:   2.419


  6 in total

1.  Control of Salmonella enteritidis infections in poultry by polymyxin B and trimethoprim.

Authors:  M C Goodnough; E A Johnson
Journal:  Appl Environ Microbiol       Date:  1991-03       Impact factor: 4.792

2.  Binding and neutralization of bacterial lipopolysaccharide by colistin nonapeptide.

Authors:  H S Warren; S A Kania; G R Siber
Journal:  Antimicrob Agents Chemother       Date:  1985-07       Impact factor: 5.191

3.  Binding and neutralization of endotoxin by Limulus antilipopolysaccharide factor.

Authors:  H S Warren; M L Glennon; N Wainwright; S F Amato; K M Black; S J Kirsch; G R Riveau; R I Whyte; W M Zapol; T J Novitsky
Journal:  Infect Immun       Date:  1992-06       Impact factor: 3.441

4.  Antibiotic-induced bacterial cell lysis: a therapeutic dilemma.

Authors:  J L Shenep
Journal:  Eur J Clin Microbiol       Date:  1986-02       Impact factor: 3.267

5.  Polymyxin B sulphate protects cats against the haemodynamic and metabolic effects of E. coli endotoxin.

Authors:  B Hughes; B R Madan; J R Parratt
Journal:  Br J Pharmacol       Date:  1981-11       Impact factor: 8.739

6.  Reducing the endotoxic activity of pertussis vaccine.

Authors:  R M Bannatyne; R Cheung
Journal:  J Hyg (Lond)       Date:  1981-12
  6 in total

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