Literature DB >> 23200295

Late response to patient-reported outcome questionnaires after surgery was associated with worse outcome.

Andrew Hutchings1, Kirstin Grosse Frie, Jenny Neuburger, Jan van der Meulen, Nick Black.   

Abstract

OBJECTIVES: Nonresponse to patient-reported outcome (PRO) questionnaires after surgery might bias the results. Our aim was to gauge the potential impact of nonresponse bias by comparing the outcomes of early and late responders. STUDY DESIGN AND
SETTING: This study compares 59,565 early and 20,735 late responders who underwent a hip or knee replacement, hernia repair, or varicose vein (VV) surgery. The association between timeliness of response and three outcomes (the mean postoperative disease-specific PRO and generic PRO scores and the proportion reporting a fair or poor result) was examined by regression analysis.
RESULTS: Late responders were slightly more likely to be young, nonwhite, deprived, and have a more severe preoperative condition with poorer quality of life. Late response was associated with a slightly poorer outcome in all four procedures although not statistically significant (P < 0.05) for VV surgery. Adjusting for preoperative characteristics reduced the strength of the associations, but they remained statistically significant.
CONCLUSION: As nonresponse to PRO questionnaires introduces slight bias, differences in response rates between hospitals should be taken into account when making comparisons so as to avoid overestimating the performance of those with lower response rates and failing to detect poor performing hospitals.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23200295     DOI: 10.1016/j.jclinepi.2012.09.001

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


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